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Merck

I5161

SAFC

碘乙酰胺

制药生产

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About This Item

线性分子式:
ICH2CONH2
CAS号:
分子量:
184.96
Beilstein:
1739080
EC號碼:
MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.21

生物源

synthetic

品質等級

化驗

≥99% (NMR)

形狀

powder

mp

92-95 °C (lit.)

溶解度

H2O: 0.5 M, clear, colorless

適合性

suitable for manufacturing use

儲存溫度

2-8°C

SMILES 字串

NC(=O)CI

InChI

1S/C2H4INO/c3-1-2(4)5/h1H2,(H2,4,5)

InChI 密鑰

PGLTVOMIXTUURA-UHFFFAOYSA-N

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一般說明

我们用于生物制药加工的SAFC® 系列优质原料经过严格的质量控制流程,配合记录文件和技术专长帮助我们的客户达到M-Clarity Program规定的要求。

M-Clarity Program

我们全面的上游工艺化学品系列不仅为生物制药生产商提供生产传统和创新治疗药物所需的优质原料,而且帮助他们更快地将产品投放市场并简化监管问题。请相信我们能够为您带来透明的供应链和可靠的全球采购能力,以最佳的法规支持和服务简化您的产品认证。

生化/生理作用

碘乙酰胺在肽测序中胱氨酸残基的烷基化试剂。它是活性位点上含有胱氨酸的酶的的一种不可逆抑制剂。它与组氨酸残基的反应速度要慢得多,但这种活性是核糖核酸酶抑制的原因。

法律資訊

SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

象形圖

Skull and crossbonesHealth hazard

訊號詞

Danger

危險分類

Acute Tox. 3 Oral - Aquatic Chronic 4 - Resp. Sens. 1 - Skin Sens. 1

儲存類別代碼

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Bypass of foregut secreted factors promoting insulin resistance is hypothesized to be one of the mechanisms by which resolution of type 2 diabetes (T2D) follows roux-en-y gastric bypass (GBP) surgery. To identify insulin resistance-associated proteins and metabolites which decrease more
Valentina R Minciacchi et al.
Oncotarget, 6(13), 11327-11341 (2015-04-11)
Large oncosomes (LO) are atypically large (1-10 µm diameter) cancer-derived extracellular vesicles (EVs), originating from the shedding of membrane blebs and associated with advanced disease. We report that 25% of the proteins, identified by a quantitative proteomics analysis, are differentially
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Neuromuscular disorders : NMD, 24(7), 563-573 (2014-05-13)
Diagnosis of muscular dystrophies is currently based on invasive methods requiring muscle biopsies or blood tests. The aim of the present study was to identify urinary biomarkers as a diagnostic tool for muscular dystrophies. Here, the urinary proteomes of Duchenne
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Arthritis research & therapy, 17, 9-9 (2015-01-21)
Smoking is a well-established risk factor for rheumatoid arthritis (RA), and it has been proposed that smoking-induced citrullination renders autoantigens immunogenic. To investigate this mechanism, we examined human lung tissue from 40 subjects with defined smoking status, with or without
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Kidney international, 86(4), 757-767 (2014-05-03)
Almost half of patients receiving lithium salts have nephrogenic diabetes insipidus. Chronic lithium exposure induces AQP2 downregulation and changes in the cellular composition of the collecting duct. In order to understand these pathophysiological events, we determined the earliest lithium targets

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