D1881

地塞米松 21-乙酸酯

≥99%

• 别名: 9α-氟-16α-甲基-11β,17α,21-三羟基--1,4-孕甾二烯-3,20-二酮-21-乙酸酯, 9α-氟-16α-甲基氢化泼尼松龙-21-乙酸酯, 泼尼松龙乙酸酯
• 经验公式（希尔记法）: C₂₄H₃₁FO₆
• CAS号: 1177-87-3
• 分子量: 434.50
• Beilstein: 2342608
• EC號碼: 214-646-8
• MDL號碼: MFCD00027407
• 分類程式碼代碼: 51422333
• PubChem物質ID: 24893562
• NACRES: NA.77

属性

• 化驗: ≥99%
• 形狀: powder
• 儲存溫度: 2-8°C
• SMILES 字串: [H][C@@]12CCC3=CC(=O)C=C[C@]3(C)[C@@]1(F)[C@@H](O)C[C@@]4(C)[C@@]2([H])C[C@@H](C)[C@]4(O)C(=O)COC(C)=O
• InChI: 1S/C24H31FO6/c1-13-9-18-17-6-5-15-10-16(27)7-8-21(15,3)23(17,25)19(28)11-22(18,4)24(13,30)20(29)12-31-14(2)26/h7-8,10,13,17-19,28,30H,5-6,9,11-12H2,1-4H3/t13-,17+,18+,19+,21+,22+,23+,24+/m1/s1
• InChI 密鑰: AKUJBENLRBOFTD-RPRRAYFGSA-N
• 基因資訊: human ... NR3C1(2908)

说明

應用

Dexamethasone 21-acetate has been used:

• as a component of the induction medium for the treatment of mice preadipocytes (5A) cells
• as a synthetic glucocorticoid to study its effects on the expression of nuclear factor erythroid 2-related factor 2 (Nrf2) and peroxiredoxin 6 (Prdx6) proteins in placentas of human and mice
• as a component of the complete medium for the culturing of porcine hepatocytes

生化／生理作用

Dexamethasone 21-acetate or dexamethasone acetate is a derivative of dexamethasone. It is a hydrophobic drug. Dexamethasone is a glucocorticoid possessing anti-inflammatory activity.

安全信息

• 象形圖: GHS08
• 訊號詞: Danger
• 危險聲明: H360FD
• 防範說明: P201 - P202 - P280 - P308 + P313 - P405 - P501
• 危險分類: Repr. 1B
• 儲存類別代碼: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• 水污染物質分類（WGK）: WGK 3
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Faceshields, Gloves