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Merck

B0390

Sigma-Aldrich

胆红素氧化酶 来源于疣孢漆斑菌

greener alternative

lyophilized powder, 15-65 units/mg protein

别名:

MvBOx, 胆红素:氧氧化还原酶

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About This Item

CAS号:
MDL编号:
UNSPSC代码:
12352204
NACRES:
NA.54

生物来源

fungus (Myrothecium verrucaria)

表单

lyophilized powder

比活

15-65 units/mg protein

组成

Protein, ≥15% biuret

储存条件

(Keep container tightly closed in a dry and well-ventilated place.)

环保替代产品特性

Waste Prevention
Design for Energy Efficiency
Learn more about the Principles of Green Chemistry.

sustainability

Greener Alternative Product

技术

toxicology assay: suitable

环保替代产品分类

运输

dry ice

储存温度

−20°C

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一般描述

我们致力于为您带来更加绿色的替代产品,这些产品遵守一项或多项绿色化学12项原则。对于生物燃料电池研究,本品已根据提高能效和防止废物原则进行了改进。详情参阅《biofiles》文章

胆红素氧化酶(BOD)属于多铜氧化酶家族亚类成员,常见于真菌。胆红素氧化酶由三个杯状(Cupredoxin-like)结构域组成,含有4个铜离子组成的2个活性位点。研究领域:细胞凋亡

应用

胆红素氧化酶用于降解胆红素。胆红素氧化酶可用于测定黄疸标本中的游离血红蛋白 。在染料流出液脱色方面也有潜在的应用,是治疗新生儿黄疸的潜在药物
胆红素氧化酶(来自疣孢漆斑菌)已用于消除胆红素干扰。它还可用于通过荧光素衍生物(FS)标记和多元校正进行直接胆红素(dBR)和总胆红素(tBR)分析。

生化/生理作用

胆红素氧化酶 (BOD) 是一种催化胆红素氧化为胆绿素的多铜氧化酶。氧是电子受体,被还原成水。在血清的医学检查中,该酶用于血清中胆红素的诊断分析。它也被用作中性条件下工作的生物燃料电池阴极的酶催化剂。是一种单体蛋白,分子量为 60 kDa,在中性 pH 下具有高反应性。BOD 参与卟啉和叶绿素代谢。
胆红素氧化酶(BOD)可氧化漆酶底物。

单位定义

在 37°C、pH 8.4 时,1 个单位每分钟将氧化 1.0 μmol 的胆红素。

象形图

Health hazard

警示用语:

Danger

危险声明

预防措施声明

危险分类

Resp. Sens. 1

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Emmanuel Suraniti et al.
Analytical chemistry, 83(7), 2824-2828 (2011-03-17)
Immobilization and electrical wiring of enzymes is of particular importance for the elaboration of efficient biosensors and can be cumbersome. Here, we report a fast and easy protocol for enzyme immobilization, and as a proof of concept, we applied it
Dan Wen et al.
Analytical chemistry, 83(10), 3968-3972 (2011-04-19)
A self-powered electrochemical sensor has been facilely designed for sensitive detection of Hg(2+) based on the inhibition of biocatalysis process of enzymatic biofuel cell (BFC) for the first time. The as-prepared one-compartment BFC, which was consisted of alcohol dehydrogenase supported
James A Cracknell et al.
Dalton transactions (Cambridge, England : 2003), 40(25), 6668-6675 (2011-05-06)
The blue multi-copper oxidase bilirubin oxidase (BOx) from the ascomycete plant pathogen Myrothecium verrucaria (Mv) efficiently catalyses the oxidation of bilirubin to biliverdin, with the concomitant reduction of O(2) to water, a reaction of considerable interest for low-temperature bio-fuel cell
Bilirubin oxidase activity of Bacillus subtilis CotA
Sakasegawa S, et al.
Applied and Environmental Microbiology, 72(1), 972-975 (2006)
Masayo Iwaki et al.
FEBS letters, 584(18), 4027-4031 (2010-08-24)
Redox-induced protonation state changes of the Glu residue in the multicopper oxidases, CueO and bilirubin oxidase (BO), were studied by attenuated total reflectance-Fourier transform infrared spectroscopy. By monitoring IR bands of the carboxylic acid C=O stretch in the wild-type and

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