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Merck
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L7386

Sigma-Aldrich

溶葡球菌酶 来源于溶葡萄球菌

≥500 units/mg protein, lyophilized powder

别名:

甘氨酰-甘氨酸内肽酶

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About This Item

CAS号:
9011-93-2
EC 号:
3.4.24.75 (BRENDA, IUBMB)
MDL號碼:
MFCD00131556
分類程式碼代碼:
12352204
NACRES:
NA.54

product name

溶葡球菌酶 来源于溶葡萄球菌, lyophilized powder, Protein 50-70 % by biuret, ≥500 units/mg protein

生物源

microbial (Staphylococcus staphylotyticus)

品質等級

300

形狀

lyophilized powder

比活性

≥500 units/mg protein

分子量

25 kDa

成份

Protein, 50-70% biuret

包裝

pkg of (sold on basis of mg protein)

溶解度

water: 2.00-2.10 mg/mL, clear to slightly hazy, colorless to light yellow

抗生素活性譜

Gram-positive bacteria

應用

diagnostic assay manufacturing
diagnostic assay manufacturing

作用方式

cell wall synthesis | interferes

運輸包裝

wet ice

儲存溫度

−20°C

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一般說明

化学结构：多肽

生化／生理作用

溶葡萄球菌素是一种分子量约为25 kDa的锌内肽酶。 由于溶葡萄球菌酶能裂解 葡萄球菌 类细胞壁肽聚糖层中的聚甘氨酸交联键，它已被发现可用于细胞裂解，并具有潜在的抗菌治疗作用。
活性最佳pH：约 7.5

單位定義

一个单位在25°C和pH 7.5条件下，在6.0 m反应混合物中可使 金黄色酿脓葡萄球菌 细胞悬浮液的浊度（A620）在10分钟内由0.250降至0.125。

象形圖

Health hazard
GHS08

訊號詞

Danger

危險聲明

H334

危險分類

Resp. Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Ian R Monk et al.
Nature communications, 10(1), 3067-3067 (2019-07-13)
WalKR (YycFG) is the only essential two-component regulator in the human pathogen Staphylococcus aureus. WalKR regulates peptidoglycan synthesis, but this function alone does not explain its essentiality. Here, to further understand WalKR function, we investigate a suppressor mutant that arose
Catherine Bennett et al.
International forum of allergy & rhinology, 9(8), 918-925 (2019-06-05)
Chronic rhinosinusitis (CRS) is a common disease, often refractory to conventional antimicrobial treatment. In this study we investigate the antimicrobial and anti-inflammatory effects of adding kappa-carrageenan to a commercially available sinus rinse. Kappa-carrageenan was added to Flo CRS and Flo
Judy J J Ou et al.
Frontiers in cellular and infection microbiology, 6, 187-187 (2017-01-14)
Background:Staphylococcus aureus (S. aureus) small colony variants (SCVs) can survive within the host intracellular milieu and are associated with chronic relapsing infections. However, it is unknown whether host invasion rates and immune responses differ between SCVs and their wild-type counterparts.
Dafne Bongiorno et al.
MicrobiologyOpen, 9(5), e1017-e1017 (2020-04-03)
Methicillin-resistant S. aureus has been reported as the main pathogen involved in chronic infections, osteomyelitis, and prosthetic joint infections. The host/pathogen interaction is dynamic and requires several changes to promote bacterial survival. Here, we focused on the internalization and persistence
Mathias Schmelcher et al.
Applied and environmental microbiology, 78(7), 2297-2305 (2012-01-31)
Staphylococci cause bovine mastitis, with Staphylococcus aureus being responsible for the majority of the mastitis-based losses to the dairy industry (up to $2 billion/annum). Treatment is primarily with antibiotics, which are often ineffective and potentially contribute to resistance development. Bacteriophage
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