跳转至内容
Merck
所有图片(1)

主要文件

查看所有文档

92131

Sigma-Aldrich

甲氧苄啶

≥99.0% (HPLC)

别名:

2,4-二氨基-5-(3,4,5-三甲氧基苄基)嘧啶, NSC 106568

登录查看公司和协议定价
所有图片(1)

About This Item

经验公式（希尔记法）:
C14H18N4O3
CAS号:
738-70-5
分子量:
290.32
Beilstein:
625127
EC 号:
212-006-2
MDL编号:
MFCD00036761
UNSPSC代码:
51285203
PubChem化学物质编号:
57653467
NACRES:
NA.85

生物来源

synthetic

质量水平

200

方案

≥99.0% (HPLC)

表单

powder

颜色

white to light yellow

mp

≥199.0 °C

抗生素抗菌谱

Gram-negative bacteria
Gram-positive bacteria
mycobacteria

作用机制

DNA synthesis | interferes
enzyme | inhibits

储存温度

2-8°C

SMILES字符串

COc1cc(Cc2cnc(N)nc2N)cc(OC)c1OC

InChI

1S/C14H18N4O3/c1-19-10-5-8(6-11(20-2)12(10)21-3)4-9-7-17-14(16)18-13(9)15/h5-7H,4H2,1-3H3,(H4,15,16,17,18)

InChI key

IEDVJHCEMCRBQM-UHFFFAOYSA-N

基因信息

human ... DHFRP1(573971) , KCNH1(3756)
rat ... Dhfr(24312)

正在寻找类似产品? 访问 产品对比指南

相关类别

一般描述

化学结构：嘧啶

应用

主要作为抗细菌剂。 二氢叶酸还原酶抑制活性和原核酶选择性。
甲氧苄啶主要用作抗菌剂。用于结核分枝杆菌的敏感性研究和流感嗜血杆菌的耐药性研究。

生化/生理作用

甲氧苄啶是一种二氢叶酸还原酶抑制剂，对原核生物酶具有选择性。
通过原核生物特异的二氢叶酸还原酶（DHFR）抑制四氢叶酸的合成。

包装

1g、5g、25g

其他说明

将容器密闭保存在干燥通风的地方。对光敏感。在惰性气体下储存。对水分敏感。产品对光和水分敏感。

象形图

Health hazardExclamation mark
GHS08,GHS07

警示用语：

Warning

危险声明

H302,H361d

危险分类

Acute Tox. 4 Oral - Repr. 2

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

个人防护装备

Eyeshields, Gloves, type N95 (US)

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000403241
0000395314
0000312685
0000312686
0000310371

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Susceptibility of Mycobacterium tuberculosis to sulfamethoxazole, trimethoprim and their combination over a 12 year period in Taiwan.
Tsi-Shu Huang1,2,3, Calvin M. Kunin, et al.
The Journal of Antimicrobial Chemotherapy, 10, 633-637 (2011)
R de Groot et al.
Antimicrobial agents and chemotherapy, 32(4), 477-484 (1988-04-01)
We studied 10 trimethoprim-resistant (Tmpr) Haemophilus influenzae isolates for which agar dilution MICs were 10 to greater than 200 micrograms/ml. Trimethoprim resistance was transferred from two Tmpr H. influenzae isolates to a Tmps strain by conjugation or transformation. Wild-type Tmpr
Kate S Baker et al.
The Lancet. Infectious diseases, 15(8), 913-921 (2015-05-06)
Shigellosis is an acute, severe bacterial colitis that, in high-income countries, is typically associated with travel to high-risk regions (Africa, Asia, and Latin America). Since the 1970s, shigellosis has also been reported as a sexually transmitted infection in men who
Karin Tegmark Wisell et al.
The Journal of antimicrobial chemotherapy, 62(1), 35-40 (2008-04-15)
The lack of oral treatment alternatives for enterococcal urinary tract infections (UTIs) has led to a renewed interest in trimethoprim. Enterococci can incorporate exogenously produced folates and thereby reverse the effect of trimethoprim. Although a large proportion of enterococci appear
Christine Manyando et al.
PloS one, 9(5), e96017-e96017 (2014-05-17)
Antibiotic therapy during pregnancy may be beneficial and impacts positively on the reduction of adverse pregnancy outcomes. No studies have been done so far on the effects of daily Co-trimoxazole (CTX) prophylaxis on birth outcomes. A phase 3b randomized trial
查看所有相关文献

商品

Folic Acid Metabolism in Cancer

Cancer research innovations address the complexity of the disease, providing advanced technologies for varied applications.

癌症中的叶酸代谢

本期生物档案回顾了我们的一些最新和最具创新性的技术及其在癌症研究中的具体应用。在准备本期生物档案时，有人指出癌症极为复杂，要确定一个与其他主题完全无关的主题极为困难。。

Folic Acid Metabolism in Cancer

Biofiles reviews innovative technologies for cancer research, reflecting the complexity of the disease.

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持