所有图片(3)
About This Item
经验公式（希尔记法）:
C17H18FN3O3
CAS号:
分子量:
331.34
Beilstein:
3568352
MDL编号:
UNSPSC代码:
41116105
PubChem化学物质编号:
NACRES:
NA.21
推荐产品
Agency
EPA 1694
质量水平
方案
≥98% (HPLC)
表单
powder or crystals
抗生素抗菌谱
Gram-negative bacteria
Gram-positive bacteria
应用
environmental
作用机制
DNA synthesis | interferes
enzyme | inhibits
SMILES字符串
OC(=O)C1=CN(C2CC2)c3cc(N4CCNCC4)c(F)cc3C1=O
InChI
1S/C17H18FN3O3/c18-13-7-11-14(8-15(13)20-5-3-19-4-6-20)21(10-1-2-10)9-12(16(11)22)17(23)24/h7-10,19H,1-6H2,(H,23,24)
InChI key
MYSWGUAQZAJSOK-UHFFFAOYSA-N
基因信息
human ... CYP1A2(1544) , KCNH1(3756)
rat ... Gabra1(29705)
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一般描述
环丙沙星是第二代广谱氟喹诺酮抗生素，具有广泛抗菌性和药动学特征，广泛用于对抗细菌感染。化学名称是1-环丙基-6-氟-4-氧代-7-(哌嗪-1-基)-1,4-二氢喹啉-3-羧酸。
化学结构：氟喹诺酮
化学结构：氟喹诺酮
应用
环丙沙星在临床中广泛用于对付革兰阳性和阴性菌，治疗皮肤、眼睛、泌尿道、下呼吸道、胃肠道等多个部位的感染。 还可联合多种抗菌药物对抗细菌生物膜和多重耐药微生物。另外，开发的衍生物可合成新型抗菌药物，疗效增强且具有抗菌、抗真菌、抗HIV、抗肿瘤和抗TB等各种抗微生物活性。
生化/生理作用
环丙沙星的作用机制是 通过抑制DNA促旋酶(gyrase)和影响细菌细胞壁来抑制细菌DNA合成 。
储存分类代码
11 - Combustible Solids
WGK
WGK 2
个人防护装备
Eyeshields, Gloves, type N95 (US)
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
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