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Merck
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文件

C9231

Sigma-Aldrich

羧苄青霉素 二钠

meets USP testing specifications

别名:

羧苄青霉素 二钠盐, α-Carboxybenzylpenicillin disodium salt 二钠盐

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About This Item

经验公式（希尔记法）:
C17H16N2Na2O6S
CAS号:
4800-94-6
分子量:
422.36
Beilstein:
5722128
EC號碼:
225-360-8
MDL號碼:
MFCD00077683
分類程式碼代碼:
51102829
PubChem物質ID:
24893142
NACRES:
NA.76

agency

USP/NF
meets USP testing specifications

品質等級

200

形狀

solid

溶解度

H2O: 50 mg/mL

抗生素活性譜

Gram-negative bacteria
Gram-positive bacteria

應用

pharmaceutical (small molecule)

作用方式

cell wall synthesis | interferes

儲存溫度

2-8°C

SMILES 字串

[Na+].[Na+].CC1(C)S[C@@H]2[C@H](NC(=O)C(C([O-])=O)c3ccccc3)C(=O)N2[C@H]1C([O-])=O

InChI

1S/C17H18N2O6S.2Na/c1-17(2)11(16(24)25)19-13(21)10(14(19)26-17)18-12(20)9(15(22)23)8-6-4-3-5-7-8;;/h3-7,9-11,14H,1-2H3,(H,18,20)(H,22,23)(H,24,25);;/q;2*+1/p-2/t9?,10-,11+,14-;;/m1../s1

InChI 密鑰

RTYJTGSCYUUYAL-YCAHSCEMSA-L

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相关类别

一般說明

Chemical structure: ß-lactam

應用

Used for selection of ampr transformed cells. Used to study the role of penicillin-sensitive transpeptidases in cell wall biosynthesis.

生化／生理作用

作用机制：羧青霉素抗生素，可通过灭活细菌细胞膜内表面的转肽酶来抑制细菌细胞壁合成（肽聚糖交联）。


抗微生物谱：具有抗革兰氏阳性和革兰氏阴性细菌活性。

分析報告

在 37°C 下可稳定保存 3 天

其他說明

Keep container tightly closed in a dry and well-ventilated place.

象形圖

Health hazard
GHS08

訊號詞

Danger

危險聲明

H317,H334

危險分類

Resp. Sens. 1 - Skin Sens. 1

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 2

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Choose from one of the most recent versions:

分析证书(COA)

Lot/Batch Number
0000297107
0000322540
0000297108
0000352376
0000352376

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Edward Avilés et al.
Organic letters, 12(22), 5290-5293 (2010-10-23)
Monamphilectine A (1), a new diterpenoid β-lactam alkaloid showing potent antimalarial activity, was isolated in milligram quantities following bioassay-directed extraction of a Puerto Rican marine sponge Hymeniacidon sp. Its structure, established by interpretation of spectral data, was confirmed unequivocally by
Yasser M Abdelrahman et al.
Nucleic acids research, 39(5), 1843-1854 (2010-11-06)
Chlamydia trachomatis is an obligate intracellular bacterium that exhibits a unique biphasic developmental cycle that can be disrupted by growth in the presence of IFN-γ and β-lactams, giving rise to an abnormal growth state termed persistence. Here we have examined
Steven D Brown et al.
Biochemistry, 48(47), 11155-11157 (2009-10-24)
Bacteriophage Qbeta coat protein forms uniform virus-like particles when expressed recombinantly in a variety of organisms. We have inserted the IgG-binding Z domain at the carboxy terminus of the coat protein and coexpressed this chimeric subunit with native coat protein
J Steinmann et al.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin, 16(33) (2011-08-30)
We describe the epidemiology and characteristics of the pathogen and patients (n=7) associated with an outbreak of a carbapenem-resistant Klebsiella pneumoniae (CRKP) strain in a German university hospital from July 2010 to January 2011. Species identification and detection of carbapenem
Brigitte K Ziervogel et al.
Structure (London, England : 1993), 21(1), 76-87 (2012-12-04)
The structure of OmpF porin in complex with three common antibiotics (zwitterionic ampicillin, anionic ertapenem, and di-anionic carbenicillin) was determined using X-ray crystallography. The three antibiotics are found to bind within the extracellular and periplasmic pore vestibules, away from the
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