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R121

Sigma-Aldrich

S(−)-Raclopride (+)-tartrate salt

>97%, solid

Sinónimos:

3,5-Dichloro-N-(1-ethylpyrrolidin-2-ylmethyl)-2-hydroxy-6-methoxybenzamide (+)-tartrate salt

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About This Item

Fórmula empírica (notación de Hill):
C15H20Cl2N2O3 · C4H6O6
Número de CAS:
98185-20-7
Peso molecular:
497.32
Número MDL:
MFCD00274072
Código UNSPSC:
12352200
ID de la sustancia en PubChem:
24277931
NACRES:
NA.77

Análisis

>97%

formulario

solid

color

white

solubilidad

H2O: 89 mg/mL

cadena SMILES

O[C@H]([C@@H](O)C(O)=O)C(O)=O.CCN1CCC[C@H]1CNC(=O)c2c(O)c(Cl)cc(Cl)c2OC

InChI

1S/C15H20Cl2N2O3.C4H6O6/c1-3-19-6-4-5-9(19)8-18-15(21)12-13(20)10(16)7-11(17)14(12)22-2;5-1(3(7)8)2(6)4(9)10/h7,9,20H,3-6,8H2,1-2H3,(H,18,21);1-2,5-6H,(H,7,8)(H,9,10)/t9-;1-,2-/m01/s1

Clave InChI

QULBVRZTKPQGCR-NDAAPVSOSA-N

Información sobre el gen

human ... DRD2(1813)

Aplicación

S(−)-Raclopride (+)-tartrate salt has been used as a D2 receptor antagonist:
  • to study the role of the D2 receptor in mediating ventrolateral PAG (vlPAG)/dorsal raphe dopaminergic antinociceptive effect in animals
  • in pharmacological and behavioral studies performed with Thap1 null mice
  • to determine the relationship between Ca2+ transients and dopamine neuron activity in rats

Acciones bioquímicas o fisiológicas

Raclopride is a benzamide derivative and a selective D2 dopamine receptor antagonist.

Envase

Bottomless glass bottle. Contents are inside inserted fused cone.

Precaución

Photosensitive

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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H Lublin et al.
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J Kopp et al.
Neuroscience, 47(4), 771-779 (1992-01-01)
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