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Merck

I3875

Sigma-Aldrich

Indoxyl sulfate potassium salt

Sinónimos:

Potassium 3-indoxyl sulfate, Urinary indican

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250 MG
44,90 €
1 G
143,00 €

44,90 €


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250 MG
44,90 €
1 G
143,00 €

About This Item

Fórmula lineal:
C8H6NO4SK
Número de CAS:
Peso molecular:
251.30
Beilstein:
3921324
Número CE:
Número MDL:
Código UNSPSC:
12352100
ID de la sustancia en PubChem:
NACRES:
NA.22

44,90 €


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Ensayo

> 98 %

Nivel de calidad

mp

165 °C (dec.) (lit.)

solubilidad

water: soluble

temp. de almacenamiento

−20°C

cadena SMILES

[K+].[O-]S(=O)(=O)Oc1c[nH]c2ccccc12

InChI

1S/C8H7NO4S.K/c10-14(11,12)13-8-5-9-7-4-2-1-3-6(7)8;/h1-5,9H,(H,10,11,12);/q;+1/p-1

Clave InChI

MDAWATNFDJIBBD-UHFFFAOYSA-M

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Descripción general

Indoxyl sulfate potassium salt is derived from indoxyl sulfate by replacing the hydrogen ion with a potassium cation. Potassium indoxyl sulfate is used as a reagent for the detection and determination of hydrogen peroxide. [1] [2] [3]

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Descripción
Precios

Código de clase de almacenamiento

11 - Combustible Solids

Clase de riesgo para el agua (WGK)

WGK 3

Punto de inflamabilidad (°F)

Not applicable

Punto de inflamabilidad (°C)

Not applicable

Equipo de protección personal

Eyeshields, Gloves, type N95 (US)


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Certificados de análisis (COA)

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Bummei Sato et al.
The American journal of cardiology, 111(5), 712-716 (2012-12-12)
The prognosis of patients with diastolic heart failure (HF) is as poor as that of patients with systolic HF. Greater chronic kidney disease-associated mortality occurs in patients with left ventricular (LV) diastolic HF than in those with systolic HF. Indoxyl
Tetsuhiro Tanaka et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 27(10), 4059-4075 (2013-06-25)
Chronic hypoxia in the tubulointerstitium serves as a final common pathway in progressive renal disease. Circumstantial evidence suggests that hypoxia-inducible factor (HIF)-1 in the ischemic tubules may be functionally inhibited in a chronic kidney disease (CKD) milieu. In this study
Binding affinity and capacity for the uremic toxin indoxyl sulfate
Devine, et al.
Toxins, 6, 416-429 (2014)
Indoxyl sulfate upregulates liver P-glycoprotein expression and activity through aryl hydrocarbon receptor signaling
Machado, et al.
Journal of the American Society of Nephrology, 29, 906-918 (2018)
Carel J Pretorius et al.
Clinica chimica acta; international journal of clinical chemistry, 419, 122-126 (2013-02-23)
The uremic toxins indoxyl sulphate (IS) and p-cresyl sulphate (pCS) are absorbed bacterial metabolites of tryptophan and tyrosine respectively and may be predictive of clinical outcome. Long chromatography times, incomplete data on the reference ranges of the free and total

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  1. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 respuesta
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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  2. How can I determine the shelf life / expiration / retest date of this product?

    1 respuesta
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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