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1125006

USP

Chlorpromazine hydrochloride

United States Pharmacopeia (USP) Reference Standard

Synonyma:

2-Chloro-10-(3-dimethylaminopropyl)phenothiazine hydrochloride, CPZ, Largactil

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About This Item

Empirický vzorec (Hillův zápis):
C17H19ClN2S · HCl
Číslo CAS:
69-09-0
Molekulová hmotnost:
355.33
Beilstein/REAXYS Number:
3779989
MDL number:
MFCD00012654
UNSPSC Code:
41116107
PubChem Substance ID:
329749339
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

chlorpromazine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

2-8°C

SMILES string

Cl[H].CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13

InChI

1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H

InChI key

FBSMERQALIEGJT-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813) , DRD3(1814) , DRD4(1815) , HTR2A(3356)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Chlorpromazine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Chlorpromazine
  • Chlorpromazine Hydrochloride
  • Chlorpromazine Hydrochloride Injection
  • Chlorpromazine Hydrochloride Oral Concentrate
  • Chlorpromazine Hydrochloride Syrup
  • Chlorpromazine Hydrochloride Tablets
Substitute for benzidine, o-dianisidine, and o-tolidine in the determination of microquantities of hemoglobin and peroxidase.

Biochem/physiol Actions

Chlorpromazine demonstrates cytotoxic and antiproliferative activity against leukemic cells, but does not affect the viability of normal lymphocytes.
Phenothiazine antipsychotic; D2 dopamine receptor antagonist, H1 histamine receptor antagonist; inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Related product

Č. produktu
Popis
Stanovení ceny

C1900000

Chlorpromazine hydrochloride, European Pharmacopoeia (EP) Reference Standard

Y0000479

Chlorpromazine impurity D, European Pharmacopoeia (EP) Reference Standard

Y0000507

Chlorpromazine impurity A, European Pharmacopoeia (EP) Reference Standard

Y0000508

Chlorpromazine impurity E, European Pharmacopoeia (EP) Reference Standard

Y0001449

Chlorpromazine impurity F, European Pharmacopoeia (EP) Reference Standard

BP467

Chlorpromazine sulfoxide, British Pharmacopoeia (BP) Reference Standard

BP856

Chlorpromazine hydrochloride, British Pharmacopoeia (BP) Reference Standard

Pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301,H330

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 3 Oral

Storage Class

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Osvědčení o analýze (COA)

Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.

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Sigma-Aldrich

D7693

Dynasore hydrate

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Sigma-Aldrich

A3085

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Sigma-Aldrich

C6628

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