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C0982

Chlorpromazine hydrochloride

Name: Chlorpromazine hydrochloride
Brand: SIAL

meets USP testing specifications

Synonyma:

2-Chloro-10-(3-dimethylaminopropyl)phenothiazine hydrochloride, CPZ, Largactil

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O této položce

Empirický vzorec (Hillův zápis):

C₁₇H₁₉ClN₂S · HCl

Číslo CAS:

69-09-0

Molekulová hmotnost:

355.33

UNSPSC Code:

41116107

NACRES:

NA.21

PubChem Substance ID:

24892290

EC Number:

200-701-3

Beilstein/REAXYS Number:

3779989

MDL number:

MFCD00012654

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Vlastnosti

biological source

synthetic (organic)

Quality Segment

200

agency

USP/NF, meets USP testing specifications

assay

98.0-101.5% dry basis

form

solid

shelf life

limited shelf life,expiry date on the label

mp

194-196 °C

solubility

water: soluble 50 g/L

application(s)

pharmaceutical (small molecule)

storage temp.

room temp

SMILES string

Cl[H].CN(C)CCCN1c2ccccc2Sc3ccc(Cl)cc13

InChI

1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H

InChI key

FBSMERQALIEGJT-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813), DRD3(1814), DRD4(1815), HTR2A(3356)

Popis

Application

Substitute for benzidine, o-dianisidine, and o-tolidine in the determination of microquantities of hemoglobin and peroxidase.

Biochem/physiol Actions

Chlorpromazine demonstrates cytotoxic and antiproliferative activity against leukemic cells, but does not affect the viability of normal lymphocytes.

Phenothiazine antipsychotic; D₂ dopamine receptor antagonist, H₁ histamine receptor antagonist; inhibits calmodulin-dependent stimulation of cyclic nucleotide phosphodiesterase and nitric oxide synthase.

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pictograms

GHS06

signalword

Danger

hcodes

H301,H330

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 3 Oral

Skladovací třída

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

flash_point_f

Not applicable

flash_point_c