1061005

Benztropine mesylate

United States Pharmacopeia (USP) Reference Standard

• Synonyma: Benztropine mesylate, Benzatropine mesylate, Benzotropine mesylate, Benztropine methanesulfonate
• Empirický vzorec (Hillův zápis): C₂₁H₂₅NO · CH₃SO₃H
• Číslo CAS: 132-17-2
• Molekulová hmotnost: 403.53
• MDL number: MFCD00074784
• UNSPSC Code: 41116107
• PubChem Substance ID: 329748912
• NACRES: NA.24

Vlastnosti

• grade: pharmaceutical primary standard
• API family: benztropine
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: CS(O)(=O)=O.CN1[C@H]2CC[C@@H]1C[C@@H](C2)OC(c3ccccc3)c4ccccc4
• InChI: 1S/C21H25NO.CH4O3S/c1-22-18-12-13-19(22)15-20(14-18)23-21(16-8-4-2-5-9-16)17-10-6-3-7-11-17;1-5(2,3)4/h2-11,18-21H,12-15H2,1H3;1H3,(H,2,3,4)/t18-,19+,20+;
• InChI key: CPFJLLXFNPCTDW-BWSPSPBFSA-N
• Gene Information: human ... CHRM1(1128)

Popis

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Benztropine mesylate USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Benztropine Mesylate Injection
• Benztropine Mesylate Tablets

Biochem/physiol Actions

Benztropine mesylate is a centrally acting muscarinic acetylcholine receptor antagonist and dopamine transporter (DAT) inhibitor (IC₅₀ = 118 nM). Benztropine mesylate has been used to treat the symptoms of Parkinson′s disease and is currently in clincial trials for chronic back pain.

Benztropine mesylate is a muscarinin acetylcholine receptor antagonist.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Bezpečnostní informace

• pictograms: GHS06
• signalword: Danger
• hcodes: H302,H311 + H331
• pcodes: P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P311
• Hazard Classifications: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 4 Oral
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable