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1478301

USP

Olanzapine

United States Pharmacopeia (USP) Reference Standard

Synonyma:

2-Methyl-4-(4-methyl-1-piperazinyl)- 10H-thieno[2,3-b][1,5]benzodiazepine

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About This Item

Empirický vzorec (Hillův zápis):
C17H20N4S
Číslo CAS:
132539-06-1
Molekulová hmotnost:
312.43
Beilstein/REAXYS Number:
7655141
MDL number:
MFCD00866702
UNSPSC Code:
41116107
PubChem Substance ID:
329750606
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

olanzapine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

CN1CCN(CC1)C2=Nc3ccccc3Nc4sc(C)cc24

InChI

1S/C17H20N4S/c1-12-11-13-16(21-9-7-20(2)8-10-21)18-14-5-3-4-6-15(14)19-17(13)22-12/h3-6,11,19H,7-10H2,1-2H3

Inchi Key

KVWDHTXUZHCGIO-UHFFFAOYSA-N

Gene Information

human ... DRD2(1813) , DRD3(1814) , DRD4(1815) , HTR2A(3356) , HTR2C(3358)

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Olanzapine USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:
  • Olanzapine and Fluoxetine Capsules
  • Olanzapine Orally Disintegrating Tablets
  • Olanzapine Tablets

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

related product

Č. produktu
Popis
Stanovení ceny

1478312

Olanzapine Related Compound A, United States Pharmacopeia (USP) Reference Standard

1478323

Olanzapine Related Compound B, United States Pharmacopeia (USP) Reference Standard

Y0001370

Olanzapine, European Pharmacopoeia (EP) Reference Standard

Y0001380

Olanzapine for system suitability, European Pharmacopoeia (EP) Reference Standard

Y0001392

Olanzapine impurity A, European Pharmacopoeia (EP) Reference Standard

1478334

Olanzapine Related Compound C, United States Pharmacopeia (USP) Reference Standard

BP1060

Olanzapine, British Pharmacopoeia (BP) Reference Standard

Y0002177

Olanzapine embonate for peak identification, CRS, European Pharmacopoeia (EP) Reference Standard

PHR2537

Olanzapine Related Compound B, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2536

Olanzapine Related Compound A, Pharmaceutical Secondary Standard; Certified Reference Material

PHR2538

Olanzapine Related Compound C, Pharmaceutical Secondary Standard; Certified Reference Material

pictograms

Skull and crossbones
GHS06

signalword

Danger

Hazard Classifications

Acute Tox. 3 Oral - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3

target_organs

Central nervous system

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

Osvědčení o analýze (COA)

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Olanzapine-d8 100 μg/mL in acetonitrile, ampule of 1 mL, certified reference material, Cerilliant®

Supelco

O-035

Olanzapine-d8

USP

USP

1478312

Olanzapine Related Compound A

USP

USP

1478334

Olanzapine Related Compound C

Risperidone ≥98% (HPLC), powder

Sigma-Aldrich

R3030

Risperidone

Rajendra P Shukla et al.
Journal of neural transmission (Vienna, Austria : 1996), 127(2), 291-299 (2020-01-08)
Olanzapine is a thienobenzodiazepine compound. It is one of the newer types of antipsychotic drugs used in the treatment of schizophrenia and other psychotic disorders. Several methods have been reported for analyzing olanzapine in its pure form or combined with
Mauricio Tohen et al.
Archives of general psychiatry, 60(11), 1079-1088 (2003-11-12)
Despite the longer duration of the depressive phase in bipolar disorder and the frequent clinical use of antidepressants combined with antipsychotics or mood stabilizers, relatively few controlled studies have examined treatment strategies for bipolar depression. To examine the use of
Jacqueline Flank et al.
Pediatric blood & cancer, 62(3), 496-501 (2014-10-21)
This retrospective review provides preliminary data regarding the safety and efficacy of olanzapine for chemotherapy-induced vomiting (CIV) control in children. Children <18 years old who received olanzapine for acute chemotherapy-induced nausea and vomiting (CINV) control from December 2010 to August
Karla Soares-Weiser et al.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 23(2), 118-125 (2012-05-29)
This comprehensive review and meta-analysis compared the effectiveness of olanzapine and other antipsychotics in schizophrenia treatment, defining effectiveness as time to all-cause medication discontinuation (primary) and as all-cause treatment discontinuation rates. This study examined randomized clinical trials (RCTs) and observational
Erin Schwenger et al.
Clinical pharmacokinetics, 50(7), 415-428 (2011-06-10)
Olanzapine, a second-generation antipsychotic, is a first-line agent in the treatment of schizophrenia. The objective of this review was to determine whether olanzapine warrants clinical pharmacokinetic monitoring in patients with schizophrenia, using a previously published decision-making algorithm. Although olanzapine is
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