M104

(±)-Muscarine chloride hydrate

≥98% (HPLC)

• Synonyma: Tetrahydro-4-hydroxy-N,N,N,5-tetramethyl-2-furanmethanammonium chloride hydrate
• Empirický vzorec (Hillův zápis): C₉H₂₀ClNO₂ · xH₂O
• Číslo CAS: 2936-25-6
• Molekulová hmotnost: 209.71 (anhydrous basis)
• MDL number: MFCD00055067
• UNSPSC Code: 12352200
• PubChem Substance ID: 24278578
• NACRES: NA.77

Vlastnosti

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• storage condition: desiccated
• color: white
• solubility: deionized water: ≥20 mg/mL
• storage temp.: room temp
• SMILES string: [Cl-].CC1OC(CC1O)C[N+](C)(C)C
• InChI: 1S/C9H20NO2.ClH/c1-7-9(11)5-8(12-7)6-10(2,3)4;/h7-9,11H,5-6H2,1-4H3;1H/q+1;/p-1
• InChI key: WUFRNEJYZWHXLC-UHFFFAOYSA-M
• Gene Information: human ... CHRM1(1128) , CHRM2(1129) , CHRM3(1131) , CHRM4(1132) , CHRM5(1133)

Popis

Application

(±)-Muscarine chloride hydrate may be used:

• as an acetylcholine receptor agonist in neuronal precursor cell lines PC 12 cells
• as toxin test compound for paper spray mass spectrometry (PSMS) optimization experiments
• as a component of quality control(QC) in hydrophilic interaction liquid chromatography-high resolution tandem mass spectrometry (HILIC-HRMS/MS) analysis of human urine samples

Biochem/physiol Actions

Muscarine is a potent agonist than acetylcholine and is not susceptible to degradation by cholinesterases. Muscarine administration results in muscle spasm especially in gut, bronchus and uterus.

Muscarinic acetylcholine receptor agonist; originally isolated from Amanita muscaria.

Features and Benefits

This compound is featured on the Acetylcholine Receptors (Nicotinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H302,H319
• pcodes: P264 - P270 - P280 - P301 + P312 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Eye Irrit. 2
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves