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15721

Sigma-Aldrich

Polydatin

≥95% (HPLC)

Synonyma:

Piceid, Reservatrol-3-β-mono-D-glucoside, Resveratrol 3-O-β-D-glucopyranoside

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
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About This Item

Empirický vzorec (Hillův zápis):
C20H22O8
Číslo CAS:
65914-17-2
Molekulová hmotnost:
390.38
Beilstein/REAXYS Number:
54837
UNSPSC Code:
12352201
PubChem Substance ID:
329750984
NACRES:
NA.25

assay

≥95% (HPLC)

form

powder

optical activity

[α]1/D -66.0±2.0° in ethanol

composition

carbon, 60.5-62.5%

storage temp.

2-8°C

SMILES string

OCC1O[C@@H](Oc2cc(O)cc(\C=C\c3ccc(O)cc3)c2)[C@H](O)[C@@H](O)[C@@H]1O

InChI

1S/C20H22O8/c21-10-16-17(24)18(25)19(26)20(28-16)27-15-8-12(7-14(23)9-15)2-1-11-3-5-13(22)6-4-11/h1-9,16-26H,10H2/b2-1+/t16?,17-,18+,19-,20-/m1/s1

InChI key

HSTZMXCBWJGKHG-AEGFYQLOSA-N

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Application

Polydatin, a type of polyphenolic phytoalexin, has many physiological and pharmacological effects including anti-inflammatory and anti-oxidative activities. Polydatin is an effective candidate drug for the protection of photo-inflammation. Polydatin exhibits therapeutic potential for vascular dementia, most likely due to its anti-oxidant activity and the direct protection of neurons.

Biochem/physiol Actions

Stilbene found in medicinal herbs. Antioxidant, anti-inflammatory and neuroprotective.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Osvědčení o analýze (COA)

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trans-Piceatannol phyproof® Reference Substance

PHL83891

trans-Piceatannol

Pinostilbene hydrate ≥95% (HPLC)

Sigma-Aldrich

SML0098

Pinostilbene hydrate

Emodin 8-glucoside ≥95% (LC/MS-UV)

Sigma-Aldrich

SMB00546

Emodin 8-glucoside

Physcion ≥98.0% (TLC)

Sigma-Aldrich

17797

Physcion

4-Bromo-Resveratrol ≥98% (HPLC)

Sigma-Aldrich

SML1078

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trans-Resveratrol United States Pharmacopeia (USP) Reference Standard

USP

1602105

trans-Resveratrol

ε-Viniferin phyproof® Reference Substance

PHL83550

ε-Viniferin

Xingmin Wang et al.
Expert opinion on investigational drugs, 22(2), 169-179 (2012-12-18)
The aim of the study was find out whether neuronal mitochondrial injury does take place in severe shock and to explore effective therapy for severe shock. Rats were divided in the following group: sham, shock + normal saline (NS), shock
Hong Zhang et al.
PloS one, 7(9), e46574-e46574 (2012-10-03)
Polydatin is one of main compounds in Polygonum cuspidatum, a plant with both medicinal and nutritional value. The possible hepatoprotective effects of polydatin on acute liver injury mice induced by carbon tetrachloride (CCl(4)) and the mechanisms involved were investigated. Intraperitoneal
Giampietro Ravagnan et al.
Inflammation, 36(1), 26-34 (2012-09-08)
It is well known that human keratinocytes produce the anti-microbial peptide β-defensin 2. Its production is enhanced by pathogenic microorganisms or other environmental stressors. In this study, we evaluated the effect of resveratrol, a polyphenol found in several dietary source
Maria Rotches-Ribalta et al.
Pharmacological research, 66(5), 375-382 (2012-08-22)
A pharmacokinetic study of the metabolic profile of resveratrol has been performed in healthy men after moderate red wine (RW) consumption. The bioavailability of resveratrol is highly influenced by several factors such as the food matrix and, therefore, this study
Hui Wen et al.
Biomedical microdevices, 14(4), 721-728 (2012-04-25)
Caenorhabditis elegans (C. elegans) is an excellent model organism for the study of aging and longevity. In this work, we presented a microfluidic approach for the evaluation of longevity in C. elegans under stress. The microfluidic device integrated multiple microvalves
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