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MAB7776

Sigma-Aldrich

Anti-Urokinase Antibody, NT fragment, clone 2G6.2

clone 2G6.2, Chemicon®, from mouse

Synonyma:

uPA

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

2G6.2, monoclonal

species reactivity

human

manufacturer/tradename

Chemicon®

technique(s)

ELISA: suitable
western blot: suitable

isotype

IgG1

NCBI accession no.

NM_002658.2

UniProt accession no.

P00749

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... PLAU(5328)

Specificity

Urokinase Plasminogen Acitivator is a serine protease (SERPIN) that converts plasminogen into the active protease plasmin. UPA is secreted from cells in as the inactive 52 kDa single chain precursor which is activated to the two chain form consisting of an alpha and beta chain.MAB7776 is specific for Human uPA, other species not tested.

Immunogen

Amino Terminal Fragment of uPA
Epitope: N-terminus fragment

Application

Detect Urokinase using this Anti-Urokinase Antibody, N-terminus fragment, clone 2G6.2 validated for use in ELISA & WB.
Research Category
Metabolism
Research Sub Category
Enzymes & Biochemistry
Western blot: 1:1000-1:3000

ELISA

Optimal working dilutions must be determined by end user.

Physical form

Format: Purified
Purified immunoglobulin. Liquid in 0.02 M phosphate buffer containing 0.25 M NaCl2 and 0.1% NaN3.

Storage and Stability

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 6 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable

Osvědčení o analýze (COA)

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Danupon Nantajit et al.
Oncology letters, 21(5), 423-423 (2021-04-15)
Cervical cancer remains a major health threat. Urokinase serves as a marker of metastatic tumors. The present study aimed to determine whether the expression levels of urokinase plasminogen activator (uPA) and urokinase plasminogen activator receptor (uPAR), before and during the
Xuehui Hong et al.
Nucleic acids research, 44(18), 8855-8869 (2016-08-28)
SOX9 encodes a transcription factor that governs cell fate specification throughout development and tissue homeostasis. Elevated SOX9 is implicated in the genesis and progression of human tumors by increasing cell proliferation and epithelial-mesenchymal transition. We found that in response to

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