8.21027

Phthaldialdehyde

for synthesis

• Synonyma: Phthaldialdehyde, OPA
• Lineární vzorec: C₆H₄-1,2-(CHO)₂
• Číslo CAS: 643-79-8
• Molekulová hmotnost: 134.13
• MDL number: MFCD00003335
• UNSPSC Code: 12352114
• EC Index Number: 211-402-2
• NACRES: NA.22

Vlastnosti

• Quality Level: 200
• assay: ≥97.5% (GC)
• form: solid
• autoignition temp.: 480 °C
• potency: 178 mg/kg LD₅₀, oral (Rat); >2000 mg/kg LD₅₀, skin (Rat)
• pH: 7 (20 °C, 53 g/L in H₂O)
• bp: 83-84 °C/1 hPa
• mp: 52-58 °C
• transition temp: flash point 132 °C
• solubility: 53 g/L
• density: 1.13 g/cm³ at 20 °C
• bulk density: 530 kg/m³
• storage temp.: 2-30°C
• InChI: 1S/C8H6O2/c9-5-7-3-1-2-4-8(7)6-10/h1-6H
• InChI key: ZWLUXSQADUDCSB-UHFFFAOYSA-N

Popis

Application

• An investigation of o-phthaldialdehyde as a derivatization reagent and optimization of instrumental parameters for qualitative amino acid profiling via UPLC-UV Detailed examination of o-phthaldialdehyde′s efficiency in amino acid profiling to enhance diagnostic accuracies for metabolic diseases like AKU and PKU (A Aspö - 2023). Access the study.


• Correlation of the Free Amino Nitrogen and Nitrogen by O-Phthaldialdehyde Methods in the Assay of Beer This research correlates nitrogen content measurements in beer using the o-phthaldialdehyde method, discussing its implications for brewing quality control (L Otama, S Tikanoja, H Kane, S Hartikainen, L Kaski - Date not specified). Access the study.


• Turn-on fluorescence detection of glutathione based on o-phthaldialdehyde-assisted SiO2 particles Investigation into a novel fluorometric method for detecting glutathione in supplements using o-phthaldialdehyde and functionalized silica particles (P Nedeljko, M Turel, A Lobnik - 2018). Access the study.


• Biochemical Measures of Neuropathy-Glutathione Assay (GSH) A study on the biochemical assessment of neuropathy by measuring glutathione levels using o-phthaldialdehyde in a methanol solution, emphasizing the methodology′s sensitivity and reliability (E Feldman - 2019). Access the study.

Analysis Note

Assay (GC, area%): ≥ 97.5 % (a/a)
Melting range (lower value): ≥ 52 °C
Melting range (upper value): ≤ 56 °C
Identity (IR): passes test

Bezpečnostní informace

• pictograms: GHS05,GHS06,GHS09
• signalword: Danger
• hcodes: H301 - H314 - H317 - H335 - H410
• pcodes: P260 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials
• wgk_germany: WGK 3
• flash_point_f: 269.6 °F - closed cup
• flash_point_c: 132 °C - closed cup