D2625

Dansyl chloride

BioReagent, suitable for amino acid labeling, powder and chunks, ≥99% (HPLC)

• Synonyma: 5-(Dimethylamino)naphthalene-1-sulfonyl chloride, DNSCl
• Empirický vzorec (Hillův zápis): C₁₂H₁₂ClNO₂S
• Číslo CAS: 605-65-2
• Molekulová hmotnost: 269.75
• Beilstein/REAXYS Number: 2217205
• EC Number: 210-092-6
• MDL number: MFCD00003985
• UNSPSC Code: 12352101
• PubChem Substance ID: 24893700
• NACRES: NA.26

Vlastnosti

• product line: BioReagent
• assay: ≥99% (HPLC)
• form: powder and chunks
• color: yellow to yellow-orange
• mp: 72-74 °C (lit.)
• solubility: acetone: 20 mg/mL
• suitability: suitable for amino acid labeling
• storage temp.: 2-8°C
• SMILES string: CN(C)c1cccc2c(cccc12)S(Cl)(=O)=O
• InChI: 1S/C12H12ClNO2S/c1-14(2)11-7-3-6-10-9(11)5-4-8-12(10)17(13,15)16/h3-8H,1-2H3
• InChI key: XPDXVDYUQZHFPV-UHFFFAOYSA-N

Popis

Application

Dansyl chloride has been used:

• as a fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase high performance liquid chromatography (HPLC)
• in the derivatization of plasma samples
• in the quantification of immobilized alkaline phosphatase

A fluorogenic reagent for fluorescent N-terminal derivatization of amino acids and peptides and detection by reverse phase HPLC.

Biochem/physiol Actions

Dansyl chloride is a sulfonyl chloride compound. It is used to end tag amino groups of peptides and proteins. Dansyl chloride is used for derivatization of free amino acids and amines in neural samples and biological fluids. It is used to study fluorescent conjugates of albumin, protein conformational changes studies and active site characterization.

Bezpečnostní informace

• pictograms: GHS05
• signalword: Danger
• hcodes: H290,H314
• pcodes: P234 - P260 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338
• Hazard Classifications: Eye Dam. 1 - Met. Corr. 1 - Skin Corr. 1B
• Storage Class: 8A - Combustible corrosive hazardous materials
• wgk_germany: WGK 3
• ppe: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges