Přejít k obsahu
Merck
Všechny fotografie(1)

Key Documents

36-011

Sigma-Aldrich

Anti-nitro-α/β-Synuclein Antibody, clone nSyn12

clone nSyn12, Upstate®, from mouse

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
Všechny fotografie(1)

About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

mouse

Quality Level

100

antibody form

ascites fluid

antibody product type

primary antibodies

clone

nSyn12, monoclonal

species reactivity

human

manufacturer/tradename

Upstate®

technique(s)

immunohistochemistry: suitable
western blot: suitable

NCBI accession no.

NM_000345.2
NM_007308.1

UniProt accession no.

P37840
Q16143

shipped in

dry ice

Gene Information

human ... SNCA(6622)

Specificity

α-Synuclein nitrated at Tyr125 and Tyr136
β-Synuclein nitrated at Tyr130

Application

Anti-nitro-α/β-Synuclein Antibody, clone nSyn12 is an antibody against nitro-α/β-Synuclein for use in WB, IH.

Quality

rountinely evaluated on recombinant protein nitrated in vitro

Target description

α-Synuclein, Mr 14.5kDa
β-Synuclein, Mr 17kDa

Physical form

Format: Unpurified

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Ještě jste nenalezli správný produkt?  

Vyzkoušejte náš produkt Nástroj pro výběr produktů.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

Osvědčení o analýze (COA)

Vyhledejte osvědčení Osvědčení o analýze (COA) zadáním čísla šarže/dávky těchto produktů. Čísla šarže a dávky lze nalézt na štítku produktu za slovy „Lot“ nebo „Batch“.

Již tento produkt vlastníte?

Dokumenty související s produkty, které jste v minulosti zakoupili, byly za účelem usnadnění shromážděny ve vaší Knihovně dokumentů.

Navštívit knihovnu dokumentů

Bregje W M de Wildt et al.
Biotechnology and bioengineering, 120(7), 2013-2026 (2023-05-06)
The transition in the field of bone tissue engineering from bone regeneration to in vitro models has come with the challenge of recreating a dense and anisotropic bone-like extracellular matrix (ECM). Although the mechanism by which bone ECM gains its
J M Souza et al.
The Journal of biological chemistry, 275(24), 18344-18349 (2000-04-05)
Intracellular proteinaceous aggregates are hallmarks of many common neurodegenerative disorders, and recent studies have shown that alpha-synuclein is a major component of several pathological intracellular inclusions, including Lewy bodies in Parkinson's disease (PD) and glial cell inclusions in multiple system
Nicole Willems et al.
BMC veterinary research, 12, 10-10 (2016-01-14)
Intervertebral disc (IVD) disease is a common spinal disorder in dogs and degeneration and inflammation are significant components of the pathological cascade. Only limited studies have studied the cytokine and chemokine profiles in IVD degeneration in dogs, and mainly focused
Emilio Fernández-Espejo et al.
Antioxidants (Basel, Switzerland), 10(5) (2021-06-03)
Background. Salivary α-synuclein (aSyn) and its nitrated form, or 3-nitrotyrosine-α-synuclein (3-NT-αSyn), hold promise as biomarkers for idiopathic Parkinson's disease (IPD). Nitrative stress that is characterized by an excess of 3-nitrotyrosine proteins (3-NT-proteins) has been proposed as a pathogenic mechanism in
Ashley D Reynolds et al.
Journal of neurochemistry, 104(6), 1504-1525 (2007-11-27)
Microglial neuroinflammatory processes play a primary role in dopaminergic neurodegeneration for Parkinson's disease (PD). This can occur, in part, by modulation of glial function following activation by soluble or insoluble modified alpha-synuclein (alpha-syn), a chief component of Lewy bodies that
Zobrazit všechny související dokumenty

Náš tým vědeckých pracovníků má zkušenosti ve všech oblastech výzkumu, včetně přírodních věd, materiálových věd, chemické syntézy, chromatografie, analytiky a mnoha dalších..

Obraťte se na technický servis.