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Hlavní dokumenty

850468P

Avanti

18:0-18:2 PC

1-stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine, powder

Synonyma:

1-octadecanoyl-2-(9Z,12Z-octadecadienoyl)-sn-glycero-3-phosphocholine; PC(18:0/18:2(9Z,12Z))

Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen


About This Item

Empirický vzorec (Hillův zápis):
C44H84NO8P
Číslo CAS:
Molekulová hmotnost:
786.11
MDL number:
UNSPSC Code:
51191904
NACRES:
NA.25

assay

>99% (TLC)

form

powder

packaging

pkg of 2 × 100 mg (850468P-200mg)
pkg of 1 × 25 mg (850468P-25mg)

manufacturer/tradename

Avanti Research - A Croda Brand 850468P

lipid type

phospholipids
cardiolipins

shipped in

dry ice

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\C/C=C\CCCCC)=O)COC(CCCCCCCCCCCCCCCCC)=O)=O

InChI

1S/C44H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h15,17,21,23,42H,6-14,16,18-20,22,24-41H2,1-5H3/b17-15-,23-21-/t42-/m1/s1

InChI key

FORFDCPQKJHEBF-VPUSDGANSA-N

General description

18:0-18:2 phosphatidylcholine (PC) has a saturated fatty acid at the sn-1 position, unsaturated fatty acid at the sn-2 position and phosphate-containing polar group at the sn-3 position. PC is a zwitterionic phospholipid. PC is synthesized by Kennedy pathway from choline.

Application

18:0-18:2 PC is suitable for use:
  • in the preparation of large unilamellar vesicles
  • in the preparation of liposomes
  • to prepare oxidised phospholipid by 2,2′-azobis(2-amidinopropane) dihydrochloride (AAPH) for multiple reaction monitoring (MRM) analysis

Biochem/physiol Actions

Phosphatidylcholine is one of the major glycerophospholipids of the eukaryotic membranes. It is essential for maintaining the structure and functions of the membrane. PC is the substrate for sphingomyelin synthesis. PC is the precursor for various second messenger like phosphatidic acid, lysophosphatidic acid, diacylglycerol.

Packaging

5 mL Clear Glass Sealed Ampule (850468P-200mg)
5 mL Clear Glass Sealed Ampule (850468P-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Storage Class

11 - Combustible Solids


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Archives of biochemistry and biophysics, 373(1), 102-109 (2000-01-06)
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Z Djuric et al.
Journal of biochemical and molecular toxicology, 15(2), 114-119 (2001-04-03)
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