840514C

16:0-18:1 Phosphatidylethanol

Avanti Research^™ - A Croda Brand 840514C

• Synonyma: 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanol (sodium salt)
• Empirický vzorec (Hillův zápis): C₃₉H₇₄NaO₈P
• Číslo CAS: 322647-55-2
• Molekulová hmotnost: 724.96
• UNSPSC Code: 12352211
• NACRES: NA.25

Vlastnosti

• assay: >99% (TLC)
• form: liquid
• packaging: pkg of 1 × 2.5 mL (840514C-25mg)
• manufacturer/tradename: Avanti Research^™ - A Croda Brand 840514C
• concentration: 10 mg/mL (840514C-25mg)
• shipped in: dry ice
• storage temp.: −20°C
• SMILES string: [H][C@@](COP([O-])(OCC)=O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCCCCCCCCCC)=O.[Na+]
• InChI: 1S/C39H75O8P.Na/c1-4-7-9-11-13-15-17-19-20-22-24-26-28-30-32-34-39(41)47-37(36-46-48(42,43)45-6-3)35-44-38(40)33-31-29-27-25-23-21-18-16-14-12-10-8-5-2;/h19-20,37H,4-18,21-36H2,1-3H3,(H,42,43);/q;+1/p-1/b20-19-;/t37-;/m1./s1
• InChI key: JFUGSRIBTPUDOW-VYMFHCNISA-M

Popis

General description

Phosphatidylethanol (PEth) is a phospholipid, that is generated in the the presence of ethanol in cell membranes. PEths like PEth 16:0/18:1, PEth 18:1/18:1, and PEth 16:0/16:0 possesses a common phosphoethanol head. Two fatty acid chains of variable length and degree of saturation are bound to this head group. It is widely distributed in gram-positive organisms.

Phosphatidylethanol (PEth) represents a group of glycerophospholipid homologues generated by substitution of ethanol for the lipid headgroup by the phospholipase D enzyme. Since the formation of PEth is specifically dependent on ethanol, the diagnostic specificity of PEth as an alcohol biomarker is theoretically 100%.

Application

16:0-18:1 Phosphatidylethanol is suitable for use in the preparation of liposomes used for permeability studies.

Biochem/physiol Actions

Phosphatidylethanols (PEths) serves as crucial biomarkers of alcohol consumption.

Packaging

5 mL Clear Glass Sealed Ampule (840514C-25mg)

Legal Information

Avanti Research is a trademark of Avanti Polar Lipids, LLC

Bezpečnostní informace

• pictograms: GHS06,GHS08
• signalword: Danger
• hcodes: H302,H315,H319,H331,H336,H351,H361d,H372,H412
• pcodes: P201 - P273 - P301 + P312 + P330 - P302 + P352 - P304 + P340 + P311 - P308 + P313
• Hazard Classifications: Acute Tox. 3 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 3 - Carc. 2 - Eye Irrit. 2 - Repr. 2 - Skin Irrit. 2 - STOT RE 1 - STOT SE 3
• target_organs: Central nervous system, Liver,Kidney
• wgk_germany: WGK 3