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W502200

Sigma-Aldrich

Phytol

≥97%, FG

Synonyma:

3,7,11,15-Tetramethyl-2-hexadecen-1-ol

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About This Item

Lineární vzorec:
CH3[CH(CH3)(CH2)3]3C(CH3)=CHCH2OH
Číslo CAS:
7541-49-3
Molekulová hmotnost:
296.53
FEMA Number:
4196
Beilstein/REAXYS Number:
1726098
EC Number:
Z-7541493
MDL number:
MFCD00002919
UNSPSC Code:
12164502
PubChem Substance ID:
24902007
NACRES:
NA.21
organoleptic:
balsam; floral
grade:
FG
biological source:
synthetic
food allergen:
no known allergens

biological source

synthetic

grade

FG

reg. compliance

EU Regulation 1334/2008 & 872/2012

assay

≥97%

refractive index

n20/D 1.463 (lit.)

bp

202-204 °C/10 mmHg (lit.)

density

0.85 g/mL at 25 °C (lit.)

application(s)

flavors and fragrances

documentation

see Safety & Documentation for available documents

food allergen

no known allergens

organoleptic

balsam; floral

SMILES string

CC(C)CCCC(C)CCCC(C)CCC\C(C)=C\CO

InChI

1S/C20H40O/c1-17(2)9-6-10-18(3)11-7-12-19(4)13-8-14-20(5)15-16-21/h15,17-19,21H,6-14,16H2,1-5H3/b20-15+

InChI key

BOTWFXYSPFMFNR-HMMYKYKNSA-N

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General description

Phytol is a diterpene alcohol commonly used as an aromatic ingredient in many fragrance compounds. In nature, it is found as a part of chlorophyll, vitamin K, vitamin E, and other tocopherols. Some of its lipophilic analogs show potent antitubercular activity.

Application


  • Zein/fucoidan-coated phytol nanoliposome: preparation, characterization, physicochemical stability, in vitro release, and antioxidant activity.: This article explores the development of phytol-loaded nanoliposomes, evaluating their stability, release profile, and antioxidant activity, demonstrating their potential in pharmaceutical applications (Chen et al., 2024).

  • Ethanolic extract of Euphorbia royleana Boiss. reduces metastasis of breast cancer cells and inhibits tumor progression in vivo.: This research demonstrates the anti-cancer properties of Euphorbia royleana, with phytol identified as one of the active compounds contributing to the inhibition of cancer cell metastasis and tumor progression (Gull et al., 2024).

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H315,H413

Hazard Classifications

Aquatic Chronic 4 - Skin Irrit. 2

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

368.6 °F

flash_point_c

187 °C

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter

Vyberte jednu z posledních verzí:

Osvědčení o analýze (COA)

Lot/Batch Number
SHBR8604
SHBR4442
SHBS3096
SHBS0285
SHBQ8987

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Sigma-Aldrich

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Terpinolene ≥95%, FG

Sigma-Aldrich

W304603

Terpinolene

Terpene Mix B certified reference material, 2000 μg/mL each component in methanol, ampule of 1 mL

Supelco

CRM40937

Terpene Mix B

Fragrance material review on phytol.
McGinty D, et al.
Food And Chemical Toxicology, 48, S59-S63 (2010)
Josué de Moraes et al.
PLoS neglected tropical diseases, 8(1), e2617-e2617 (2014-01-07)
Schistosomiasis is a major endemic disease that affects hundreds of millions worldwide. Since the treatment and control of this parasitic disease rely on a single drug, praziquantel, it is imperative that new effective drugs are developed. Here, we report that
Identification of fatty aldehyde dehydrogenase in the breakdown of phytol to phytanic acid
van den Brink DM, et al.
Molecular genetics and metabolism reports, 82(1), 33-37 (2004)
Antitubercular potential of some semisynthetic analogues of phytol.
Saikia D, et al.
Bioorganic & Medicinal Chemistry Letters, 20(2), 508-512 (2010)
Chiara Baccelli et al.
Journal of natural products, 70(6), 910-917 (2007-06-06)
The diterpenes previously isolated from the leaves of Croton zambesicus were tested to evaluate their vasorelaxant activity on the Wistar rat aorta. Their vasorelaxant effect was compared to a series of synthetic trachylobanes and related polycyclic compounds on KCl- or
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