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900404

Sigma-Aldrich

SLAP HydroPyridopyrazine Reagent

≥95%

Synonyma:

(1-((Trimethylsilyl)methyl)piperidin-2-yl)methanamine

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About This Item

Empirický vzorec (Hillův zápis):
C10H24N2Si
Číslo CAS:
2023645-22-7
Molekulová hmotnost:
200.40
UNSPSC Code:
12352103
PubChem Substance ID:
329769829
NACRES:
NA.22

assay

≥95%

form

liquid

refractive index

n/D 1.4470

density

0.9030 g/mL

functional group

amine

storage temp.

−20°C

Application

Silicon amine protocol (SLAP) reagents, in conjunction with aldehydes and ketones, form N-unprotected piperazines via photocatalytic cross-coupling with Ir[(ppy)2dtbbpy]PF6 (747769). Heteroaromatic, aromatic, and aliphatic aldehydes are well tolerated, as are structurally and stereochemically complex SLAP reagents. This product was introduced in collaboration with the Bode Research Group and provides a tin-free alternative to SnAP (tin amine protocol) reagents for piperazine synthesis.

Other Notes

Related product

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Popis
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798916

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798878

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798851

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798843

SnAP 3Me-M Reagent

804088

SnAP 2-Spiro-(4-Pip) M Reagent

804142

SnAP 3-Spiro-(4-Pip) M Reagent

804177

SnAP 3-Spiro-(2-Pyr) M Reagent

804185

SnAP 2-Spiro-(2-Pyr) M Reagent

804150

SnAP 2,3-Bicyclo-(3,4-Pyr) M Reagent

900402

SLAP HydroQuinoxaline, 95%

900401

SLAP 2,3-Bicyclo-(3,4-THF) N-BnPip Reagent, ≥95%

900403

SLAP HydroPyrrolopyrazine Reagent

900406

SLAP N-Bn-3Me-Pip Reagent

900755

SLAP TA, 95%

900756

SLAP M, ≥95%

900814

SLAP TM, ≥95%

900815

SLAP 5-TMS TM, ≥95%

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

175.0 °F

flash_point_c

79.44 °C

Vyberte jednu z posledních verzí:

Osvědčení o analýze (COA)

Lot/Batch Number
MKCB4107

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Protokoly

SiLicon Amine Protocol (SLAP) Reagents

The expanding class of SLAP reagents provides access to saturated N-heterocycles and aliphatic aldehydes and ketones without additional reagents or the generation of toxic byproducts.

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