531537
1,2-Epoxy-2-methylpropane
97%
Synonyma:
1,2-Epoxy-isobutane, 2,2-Dimethyloxirane, Isobutylene oxide
Přihlásitk zobrazení cen stanovených pro organizaci a smluvních cen
About This Item
Empirický vzorec (Hillův zápis):
C4H8O
Číslo CAS:
Molekulová hmotnost:
72.11
EC Number:
MDL number:
UNSPSC Code:
12162002
PubChem Substance ID:
NACRES:
NA.23
Doporučené produkty
assay
97%
refractive index
n20/D 1.374 (lit.)
bp
50-51 °C (lit.)
density
0.812 g/mL at 25 °C (lit.)
SMILES string
CC1(C)CO1
InChI
1S/C4H8O/c1-4(2)3-5-4/h3H2,1-2H3
InChI key
GELKGHVAFRCJNA-UHFFFAOYSA-N
Související kategorie
General description
1,2-Epoxy-2-methylpropaneis a versatile epoxide monomer that is used to prepare polyether-based polymers.These polymers can be used in the production of hydrogels and other polymericmaterials that are used in drug delivery systems, tissue engineering, andmedical devices. Additionally, 1,2-epoxy-2-methylpropane can beused to modify existing polymer backbones for enhancing their biocompatibilityand performance in biomedical applications.
Application
1,2-Epoxy-2-methylpropane can be used in the synthesis of novel semicrystalline polyesters through copolymerization with cyclic anhydrides. These polyesters exhibit desirable thermal properties, including high melting temperatures and enhanced mechanical strength. These properties make them suitable for various applications including tissue engineering, surgical implants, and bioelectronics.
signalword
Danger
hcodes
Hazard Classifications
Carc. 2 - Flam. Liq. 2 - Muta. 2 - Skin Corr. 1C
Storage Class
3 - Flammable liquids
wgk_germany
WGK 1
flash_point_f
-26.5 °F
flash_point_c
-32.5 °C
ppe
Eyeshields, Faceshields, Gloves
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M Cornet et al.
Archives of toxicology, 65(4), 263-267 (1991-01-01)
Until now, no data are available concerning the biotransformation and toxicity of 2-methylpropene (or isobutene), a gaseous alkene widely used in industry (rubber, fuel additives, plastic polymers, adhesives, antioxidants). In this work, the biotransformation of 2-methylpropene (MP) has been studied
M Cornet et al.
Chemical research in toxicology, 8(7), 987-992 (1995-10-01)
The biotransformation of 2-methylpropene, a gaseous alkene widely used in industry, was investigated in vitro in liver tissue of rats, mice, and humans. Interspecies comparison revealed that the lowest levels of the primary epoxide metabolite were detected in incubations of
Paul R Carlier et al.
The Journal of organic chemistry, 71(4), 1592-1597 (2006-02-14)
Protonated epoxides feature prominently in organic chemistry as reactive intermediates. Herein, we describe 10 protonated epoxides using B3LYP, MP2, and CCSD/6-311++G calculations. Relative to CCSD, B3LYP consistently overestimates the C2-O bond length. Protonated 2-methyl-1,2-epoxypropane is the most problematic species studied
U Jorritsma et al.
Mutagenesis, 10(2), 101-104 (1995-03-01)
2-Methylpropene (isobutene), a gaseous compound widely used in chemical industries, is metabolized to the epoxide 2-methyl-1,2-epoxypropane. The parent compound has previously been shown to be non-mutagenic in a modified Ames test, whereas the epoxide metabolite gave a positive result. In
M Cornet et al.
Mutation research, 271(3), 213-221 (1992-06-01)
The mutagenic properties of 2-methylpropene (MP) and 2-methyl-1,2- epoxypropane (MEP) were investigated in the Salmonella assay. A simple exposure system, consisting of gastight tissue culture flasks, was used. This method has the advantage that the volatile test chemical is present
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