301981

5,6,7,8-Tetrahydroisoquinoline

95%

• Empirický vzorec (Hillův zápis): C₉H₁₁N
• Číslo CAS: 36556-06-6
• Molekulová hmotnost: 133.19
• EC Number: 253-098-4
• MDL number: MFCD00012168
• UNSPSC Code: 12352100
• PubChem Substance ID: 24858223
• NACRES: NA.22

Vlastnosti

• assay: 95%
• form: liquid
• refractive index: n20/D 1.545 (lit.)
• bp: 106-108 °C/13 mmHg (lit.)
• density: 1.03 g/mL at 25 °C (lit.)
• SMILES string: C1CCc2cnccc2C1
• InChI: 1S/C9H11N/c1-2-4-9-7-10-6-5-8(9)3-1/h5-7H,1-4H2
• InChI key: HTMGQIXFZMZZKD-UHFFFAOYSA-N

Popis

General description

Reduction of 5,6,7,8-tetrahydroisoquinoline with sodium in ethanol gives trans-decahydroquinolines. 5,6,7,8-Tetrahydroisoquinoline is also referred as Bz-tetrahydroisoquinoline.

Application

5,6,7,8-Tetrahydroisoquinoline was used in total synthesis of (±)-desoxycodeine-D. It was also used in the synthesis of 7,8-dihydroisoquinolin-5(6H)-one.

Bezpečnostní informace

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3
• flash_point_f: 212.0 °F - closed cup
• flash_point_c: 100 °C - closed cup
• ppe: Eyeshields, Gloves, type ABEK (EN14387) respirator filter