254363

Methylmagnesium iodide solution

3.0 M in diethyl ether

• Synonyma: Iodomethylmagnesium, Methylmagnesium iodine
• Lineární vzorec: CH₃MgI
• Číslo CAS: 917-64-6
• Molekulová hmotnost: 166.24
• Beilstein/REAXYS Number: 1209226
• MDL number: MFCD00001026
• UNSPSC Code: 12352103
• PubChem Substance ID: 24855379
• NACRES: NA.22

Vlastnosti

• Quality Level: 200
• reaction suitability: reaction type: Grignard Reaction
• concentration: 3.0 M in diethyl ether
• density: 1.261 g/mL at 25 °C
• SMILES string: C[Mg]I
• InChI: 1S/CH3.HI.Mg/h1H3;1H;/q;;+1/p-1
• InChI key: AUPXBVDHVRZMIB-UHFFFAOYSA-M

Popis

Application

Methylmagnesium iodide solution can be used:

• To prepare cis-1,2-dialkylcyclopropanols by treating with titanium(IV) alkoxide and carboxylic esters.
• In stereospecific Ni catalyzed Kumada cross-coupling reactions of benzylic ethers.
• To prepare 2,4-disubstituted selenochromenes by reacting with 1-benzoselenopyrylium salts.
• In one of the key synthetic steps for the preparation of 7β-methyl-substituted 5-androstene derivatives from 3β-acetoxyandrost-5-en-17-one stereoselectively.

Bezpečnostní informace

• pictograms: GHS02,GHS05,GHS07
• signalword: Danger
• hcodes: H224,H260,H314,H336
• pcodes: P210 - P231 + P232 - P233 - P280 - P303 + P361 + P353 - P305 + P351 + P338 - P403 + P233
• Hazard Classifications: Eye Dam. 1 - Flam. Liq. 1 - Skin Corr. 1B - STOT SE 3 - Water-react 1
• target_organs: Central nervous system
• supp_hazards: EUH014,EUH019
• Storage Class: 4.3 - Hazardous materials which set free flammable gases upon contact with water
• wgk_germany: WGK 3
• flash_point_f: -40.0 °F - closed cup
• flash_point_c: -40 °C - closed cup
• ppe: Faceshields, Gloves, Goggles, type ABEK (EN14387) respirator filter