45703

Erythromycin standard solution

1 mg/mL in H₂O

• Sinónimos: Erythromycin from Streptomyces erythreus
• Fórmula empírica (notación de Hill): C₃₇H₆₇NO₁₃
• Número de CAS: 114-07-8
• Peso molecular: 733.93
• Beilstein: 8183758
• Número MDL: MFCD00084654
• Código UNSPSC: 51282304
• ID de la sustancia en PubChem: 329756912
• NACRES: NA.85

Propiedades

• origen biológico: Streptomyces erythreus (strains)
• Agency: EPA 1694
• Formulario: liquid
• concentración: 1 mg/mL in H₂O
• color: colorless
• espectro de actividad antibiótica: Gram-positive bacteria
• aplicaciones: environmental
• Modo de acción: protein synthesis | interferes
• temp. de almacenamiento: 2-8°C
• cadena SMILES: CC[C@H]1OC(=O)[C@H](C)C(O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)C(C)C(OC3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)C(O)[C@]1(C)O
• InChI: 1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
• Clave InChI: ULGZDMOVFRHVEP-RWJQBGPGSA-N

Descripción

Descripción general

Chemical structure: macrolide

Aplicación

Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains. [1][2][3].

Acciones bioquímicas o fisiológicas

Mode of Action: Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site by binding to the 50s subunit of the bacterial 70s rRNA complex.

Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria.

Envase

10 ml

Precaución

This Erythromycin solution is concentrated at 1 mg/mL in H₂O and is stable in solution at 37°C for 3 days. Stock solutions should be stored at 2-8°C.

Otras notas

Keep container tightly closed in a dry and well-ventilated place. Store under inert gas.

Información de seguridad

• Código de clase de almacenamiento: 10 - Combustible liquids
• Punto de inflamabilidad (°F): Not applicable
• Punto de inflamabilidad (°C): Not applicable
• Equipo de protección personal: Eyeshields, Gloves