SRE0023
β-Glucuronidase from abalone
Purified, aqueous solution, β-glucuronidase 150,000-250,000 units/mL, β-glucuronidase ≥20,000,000 units/g protein
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10 ML
CHF 361.00
25 ML
CHF 720.00
50 ML
CHF 1’370.00
CHF 361.00
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Cambia visualizzazione
10 ML
CHF 361.00
25 ML
CHF 720.00
50 ML
CHF 1’370.00
About This Item
Numero MDL:
Codice UNSPSC:
12352204
NACRES:
NA.54
CHF 361.00
Check Cart for Availability
Prodotti consigliati
Livello qualitativo
Stato
aqueous solution
β-glucuronidase activity
≥20,000,000 units/g protein
150,000-250,000 units/mL
secondary activity
≤7,500 units/mL sulfatase
Temperatura di conservazione
2-8°C
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Categorie correlate
Applicazioni
Technical Article Comparing Performance of Different Enzymes
Learn more
about recent application data generated by Sigma R&D to optimize hydrolysis for different drug classes using enzymes from different sources and the use of a chromatographicaly purified enzyme to reduce the effect of esterase activity resulting in conversion of 6-MAM to Morphine.
Learn more
about recent application data generated by Sigma R&D to optimize hydrolysis for different drug classes using enzymes from different sources and the use of a chromatographicaly purified enzyme to reduce the effect of esterase activity resulting in conversion of 6-MAM to Morphine.
Azioni biochim/fisiol
β-Glucuronidase (GUSB) is a lysosomal enzyme, that degrades glucuronate-containing glycosaminoglycans.[1] β-glucuronidase, obtained from abalone has the ability to hydrolyze samples, that has high analyte concentrations.[2] Absence of β-glucuronidase results in mucopolysaccharidosis type VII (MPSVII), which leads to lysosomal storage in the brain.[1]
Definizione di unità
One Sigma or modified Fishman unit will liberate 1.0 μg of phenolphthalein from phenolphthalein glucuronide per hr at 37 °C at pH 3.8 (30 min assay).
Stato fisico
Supplied as an aqueous solution containing L-proline, ammonium acetate and sodium azide
Codice della classe di stoccaggio
10 - Combustible liquids
Classe di pericolosità dell'acqua (WGK)
nwg
Punto d’infiammabilità (°F)
Not applicable
Punto d’infiammabilità (°C)
Not applicable
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I clienti hanno visto anche
Evaluation of abalone beta-glucuronidase substitution in current urine hydrolysis procedures
Malik W B, et al.
Journal of Analytical Toxicology, 38(3), 171-176 (2014)
Human beta-glucuronidase: structure, function, and application in enzyme replacement therapy
Naz H, et al.
Rejuvenation Research, 16(5), 352-363 (2013)
Articoli
β-glucuronidase (GUS) enzymes are utilized to hydrolyze glucuronide (gluc) drug metabolites to the parent drug, facilitating analysis by LC-MS/MS.
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