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P8877

Sigma-Aldrich

D-(−)-3-Phosphoglyceric acid disodium salt

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≥93% dry basis (enzymatic), powder

Sinonimo/i:

(−)-Disodium D-3-phosphoglycerate, D-Glycerate 3-phosphate disodium salt

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10 MG
CHF 30.20
1 G
CHF 491.00
5 G
CHF 1’930.00

CHF 30.20

Spedizione prevista il28 maggio 2025

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Cambia visualizzazione
10 MG
CHF 30.20
1 G
CHF 491.00
5 G
CHF 1’930.00

About This Item

Formula empirica (notazione di Hill):
C3H5Na2O7P
Numero CAS:
80731-10-8
Peso molecolare:
230.02
Beilstein:
3767836
Numero MDL:
MFCD00069569
Codice UNSPSC:
12352201
ID PubChem:
24898988
NACRES:
NA.25

CHF 30.20

Spedizione prevista il28 maggio 2025

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Origine biologica

synthetic (inorganic)

Livello qualitativo

200

Saggio

≥93% dry basis (enzymatic)

Stato

powder

Caratteristiche più verdi

Atom Economy
Design for Energy Efficiency
Use of Renewable Feedstocks
Learn more about the Principles of Green Chemistry.

sustainability

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Impurezze

<14% water (NMR)

Colore

white

Solubilità

H2O: 50 mg/mL, clear, colorless to faintly yellow

Cationi in tracce

Na: 18-22% (dry basis)

Categoria alternativa più verde

Re-engineered,

Temperatura di conservazione

−20°C

Stringa SMILE

[Na+].[Na+].O[C@H](COP(O)([O-])=O)C([O-])=O

InChI

1S/C3H7O7P.2Na/c4-2(3(5)6)1-10-11(7,8)9;;/h2,4H,1H2,(H,5,6)(H2,7,8,9);;/q;2*+1/p-2/t2-;;/m1../s1
RGCJWQYUZHTJBE-YBBRRFGFSA-L

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Applicazioni

D-(-)-3-Phosphoglyceric acid disodium salt has been used in a study to assess the phosphorylation of glyceric acid in aqueous solution. [1] It has also been used in a study to characterize a glutathione- and NAD-dependent arsenate reduction linked to glycolysis. [2]

Azioni biochim/fisiol

3-Phosphoglyceric acid is an intermediate in glycolysis. It also a precursor in the formation of serine.

Altre note

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Pittogrammi

Health hazardExclamation mark
GHS08,GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335,H371

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 2 - STOT SE 3

Organi bersaglio

Eyes,Central nervous system, Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

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Certificati d'analisi (COA)

Lot/Batch Number
0000415585
0000415585
0000399555
0000369134
0000356750

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Balázs Németi et al.
Toxicological sciences : an official journal of the Society of Toxicology, 85(2), 847-858 (2005-03-25)
Reduction of arsenate (AsV) to the more toxic arsenite (AsIII) is of high toxicological importance, yet in vivo relevant enzymes involved have not been identified. Purine nucleoside phosphorylase (PNP) is an efficient AsV reductase in vitro, but its role in
V Kolb et al.
Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life, 26(1), 7-13 (1996-02-01)
The phosphorylation of glyceric acid is an interesting prebiotic reaction because it converts a simple, potentially prebiotic organic molecule into phosphate derivatives that are central to carbohydrate metabolism. We find that 0.05 M glyceric acid in the presence of 0.5
Maria V Liberti et al.
Cell metabolism, 26(4), 648-659 (2017-09-19)
Targeted cancer therapies that use genetics are successful, but principles for selectively targeting tumor metabolism that is also dependent on the environment remain unknown. We now show that differences in rate-controlling enzymes during the Warburg effect (WE), the most prominent
Yinhua Zhang et al.
The Journal of biological chemistry, 279(35), 37185-37190 (2004-07-06)
Phosphoglycerate mutases catalyze the interconversion of 2- and 3-phosphoglycerate in the glycolytic and gluconeogenic pathways. They exist in two unrelated forms that are either cofactor (2,3-diphosphoglycerate)-dependent or cofactor-independent. The two enzymes have no similarity in amino acid sequence, tertiary structure
Jeremy M Foster et al.
PloS one, 5(10), e13576-e13576 (2010-12-29)
The glycolytic phosphoglycerate mutases exist as non-homologous isofunctional enzymes (NISE) having independent evolutionary origins and no similarity in primary sequence, 3D structure, or catalytic mechanism. Cofactor-dependent PGM (dPGM) requires 2,3-bisphosphoglycerate for activity; cofactor-independent PGM (iPGM) does not. The PGM profile
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Questions

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  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer

    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/449/386/product-dating-information-mk.pdf

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  2. How is shipping temperature determined? And how is it related to the product storage temperature?

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    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

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