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N4505

Sigma-Aldrich

β-Nicotinamide adenine dinucleotide, reduced dipotassium salt

Sinonimo/i:

β-DPNH, β-NADH, DPNH, Diphosphopyridine nucleotide, reduced form, NADH

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100 MG
CHF 104.00
500 MG
CHF 327.00
1 G
CHF 1’070.00

CHF 104.00


Spedizione prevista il31 marzo 2025


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Cambia visualizzazione
100 MG
CHF 104.00
500 MG
CHF 327.00
1 G
CHF 1’070.00

About This Item

Formula condensata:
C21H27N7O14P2K2
Numero CAS:
Peso molecolare:
741.62
Numero MDL:
Codice UNSPSC:
41106305
ID PubChem:
NACRES:
NA.51

CHF 104.00


Spedizione prevista il31 marzo 2025


Richiedi un ordine bulk

Origine biologica

synthetic

Livello qualitativo

Saggio

≥95%

Stato

powder

Solubilità

10 mM NaOH: soluble-100 mg/mL, clear to hazy, faintly yellow to yellow

Temperatura di conservazione

−20°C

Stringa SMILE

[K].NC(=O)C1=CN(C=CC1)C2OC(COP(O)(=O)OP(O)(=O)OCC3OC(C(O)C3O)n4cnc5c(N)ncnc45)C(O)C2O

InChI

1S/C21H29N7O14P2.K.H/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33;;/h1,3-4,7-8,10-11,13-16,20-21,29-32H,2,5-6H2,(H2,23,33)(H,34,35)(H,36,37)(H2,22,24,25);;
KMRPNNQOKAHXEZ-UHFFFAOYSA-N

Informazioni sul gene

human ... IMPDH2(3615)

Applicazioni

β-Nicotinamide adenine dinucleotide (NAD+) and β-Nicotinamide adenine dinucleotide, reduced (NADH) comprise a coenzyme redox pair (NAD+:NADH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. In addition to its redox function, NAD+/NADH is a donor of ADP-ribose units in ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) reactions and a precursor of cyclic ADP-ribose (ADP-ribosyl cyclases).

Azioni biochim/fisiol

Electron donor

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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Cornelia Wetzker et al.
Scientific reports, 9(1), 19534-19534 (2019-12-22)
Metabolic profiles vary across all levels of biological diversity, from cells to taxa. Two-photon fluorescence lifetime imaging microscopy (FLIM) facilitates metabolic characterisation of biological specimens by assaying the intrinsic autofluorescence of the ubiquitous coenzymes NAD(P)H and FAD. The potential of
Luisa Schwarzmann et al.
Bioscience reports, 41(1) (2021-01-05)
Nicotinamide adenine dinucleotide (NAD) is a coenzyme in metabolic reactions and cosubstrate in signaling pathways of cells. While the intracellular function of NAD is well described, much less is known about its importance as an extracellular molecule. Moreover, there is
Sritama De Sarkar et al.
Parasitology research, 118(1), 335-345 (2018-11-25)
Berberine chloride, a plant-derived isoquinoline alkaloid, has been demonstrated to have leishmanicidal activity, which is mediated by generation of a redox imbalance and depolarization of the mitochondrial membrane, resulting in a caspase-independent apoptotic-like cell death. However, its impact on mitochondrial
Erika Chacin et al.
Nature communications, 12(1), 5224-5224 (2021-09-03)
The replication of chromosomes during S phase is critical for cellular and organismal function. Replicative stress can result in genome instability, which is a major driver of cancer. Yet how chromatin is made accessible during eukaryotic DNA synthesis is poorly
Antonio Vassallo et al.
Pharmaceutics, 12(6) (2020-06-19)
The purpose of this study was to improve the knowledge on Hura crepitans L., a plant belonging to the Euphorbiaceae family that, on the one hand, is known to be toxic, but on the other, is a source of polyphenols

Questions

1–4 of 4 Questions  
  1. What information do you have on the solubility and solution stability of Product N4505, β-Nicotinamide adenine dinucleotide, reduced dipotassium salt?

    1 answer
    1. Solubility and solution stability information can be found on the product information sheet (under Documents, above).

      Helpful?

  2. What is the absorption maximum and the fluorescence emission maximum wavelengths for Product N4505, β-Nicotinamide adenine dinucleotide, reduced dipotassium salt?

    1 answer
    1. The absorption maximum for NADH is at 340 nm and the fluorescence emission maximum is at 460 nm.

      Helpful?

  3. What is the Department of Transportation shipping information for this product?

    1 answer
    1. Transportation information can be found in Section 14 of the product's (M)SDS.To access the shipping information for this material, use the link on the product detail page for the product.

      Helpful?

  4. What is the extinction coefficient for Product N4505, β-Nicotinamide adenine dinucleotide, reduced dipotassium salt?

    1 answer
    1. EmM = 6.22 (340 nm) and 14.4 (259 nm, pH 9.5)

      Helpful?

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