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C7956

Sigma-Aldrich

Coenzyme Q1

≥95%

Sinonimo/i:

2,3-Dimethoxy-5-methyl-6-(3-methyl-2-butenyl)-1,4-benzoquinone, Ubiquinone-1, Ubiquinone-5

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2 MG
CHF 151.00
10 MG
CHF 338.00
5 X 10 MG
CHF 1’360.00

CHF 151.00


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Scegli un formato

Cambia visualizzazione
2 MG
CHF 151.00
10 MG
CHF 338.00
5 X 10 MG
CHF 1’360.00

About This Item

Formula empirica (notazione di Hill):
C14H18O4
Numero CAS:
Peso molecolare:
250.29
Numero MDL:
Codice UNSPSC:
12352204
ID PubChem:
NACRES:
NA.51

CHF 151.00


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Saggio

≥95%

Stato

liquid

Temperatura di conservazione

−20°C

Stringa SMILE

COC1=C(OC)C(=O)C(C\C=C(\C)C)=C(C)C1=O

InChI

1S/C14H18O4/c1-8(2)6-7-10-9(3)11(15)13(17-4)14(18-5)12(10)16/h6H,7H2,1-5H3
SOECUQMRSRVZQQ-UHFFFAOYSA-N

Descrizione generale

Coenzyme Q (CoQ) is localized to the hydrophobic domain of the phospholipid bilayer of mitochondria, plasma lipoproteins, and other biological membranes. It is a ubiquinone homolog with a short isoprenoid side chain.[1]

Applicazioni

Coenzyme Q1 has been used to measure the mitochondrial respiratory chain complex 1 activity.[2][3][4][5]

Azioni biochim/fisiol

Coenzyme Q1 (CoQ1) is a 1 isoprenyl group (not naturally occurring) member of a family of ubiquinones that share a quinine chemical group but differ in the number of isoprenyl chemical subunits in their tail. The CoQ compounds are lipid soluble components of cell membranes where they perform multiple functions such as electron and proton transport. The most well studied CoQ compound is CoQ10. CoQ1 is frequently used in comparison studies on the effect of isoprenyl chain length on CoQ functions or distribution and to identify quinone reductases.

Altre note

Analog of coenzyme Q10 (not naturally occurring)

Codice della classe di stoccaggio

10 - Combustible liquids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)


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The lipid compositions of various regions of the human brain were investigated during aging and in Alzheimer's disease. The phospholipid amounts and compositions remained unchanged during aging. There were, however, considerable differences both in phospholipid composition and amount when the
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Questions

1–2 of 2 Questions  
  1. What is the concentration?

    1 answer
    1. Product C7956 may present as a viscous liquid. Although a specific density has not been assigned due to the product being packaged by weight, there is a predicted density for this compound which is approximately 1.10 ±0.1 g/mL. This implies that for every 10 mg of material, the volume is expected to be around 9.1 µL. The molecular weight of this product is 250.29 g/mol, resulting in a concentration of roughly 4.39 M.

      Helpful?

  2. Hi, I use CoQ1 for COX I enzyme activity assay. Can this Coenzyme Q1(C7956) dissolve in water?

    1 answer
    1. We have only tested this item's solubility in acetone at 50 mg/ml. Upon further research, this item looks to be poorly soluble in water.

      Helpful?

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