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F1641

Sigma-Aldrich

Anti-Human IgG (γ-chain specific), F(ab′)2 fragment–FITC antibody produced in goat

affinity isolated antibody, buffered aqueous solution

Sinonimo/i:

Anti-Human IgG FITC

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0.5 ML
CHF 182.00
1 ML
CHF 255.00
2 ML
CHF 555.00

CHF 182.00


Spedizione prevista il01 giugno 2025


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0.5 ML
CHF 182.00
1 ML
CHF 255.00
2 ML
CHF 555.00

About This Item

Numero MDL:
Codice UNSPSC:
12352203
NACRES:
NA.46

CHF 182.00


Spedizione prevista il01 giugno 2025


Richiedi un ordine bulk

Origine biologica

goat

Livello qualitativo

Coniugato

FITC conjugate

Forma dell’anticorpo

affinity isolated antibody

Tipo di anticorpo

secondary antibodies

Clone

polyclonal

Stato

buffered aqueous solution

tecniche

direct immunofluorescence: 1:32

Temperatura di conservazione

2-8°C

modifica post-traduzionali bersaglio

unmodified

Categorie correlate

Descrizione generale

Human IgGs are glycoprotein antibodies that contain two equivalent light chains and a pair of identical heavy chains. IgGs have four distinct isoforms, ranging from IgG1 to IgG4. These antibodies regulate immunological responses to allergy and pathogenic infections. IgGs have also been implicated in complement fixation and autoimmune disorders
Anti-Human IgG (γ-chain specific), (F(ab′)2) fragment-FITC antibody is specific for human IgG when tested against purified human IgA, IgG, IgM, Bence Jones κ and λ myeloma proteins. The use of this product prevents background staining due to the presence of Fc receptors.
Immunoglobulin G (IgG) belongs to the immunoglobulin family and is a widely expressed serum antibody. The two heavy chains and two light chains of IgG are connected by a disulfide bond. It is a glycoprotein and mainly helps in immune defense. IgG is usually found as a monomer. IgG antibody subtype is the most abundant of serum immunoglobulins of the immune system. It is secreted by B cells and is found in blood and extracellular fluids. About 70 percent of the total immunoglobulin consists of IgG. Immunoglobulin G (IgG) participates in hypersensitivity type II and type III.

Immunogeno

Purified human IgG

Applicazioni

Anti-Human IgG (γ-chain specific), (F(ab′)2) fragment-FITC antibody is suitable for use in direct immunofluorescence (1:32).
Anti-Human IgG (γ-chain specific), F(ab′)2 fragment−FITC antibody has been used in immunofluorescence studies and flow cytometric crossmatch (FCXM).

Stato fisico

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Esclusione di responsabilità

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Codice della classe di stoccaggio

12 - Non Combustible Liquids

Classe di pericolosità dell'acqua (WGK)

nwg

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


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I S Bağcı et al.
Journal of the European Academy of Dermatology and Venereology : JEADV, 33(11), 2123-2130 (2019-07-03)
Ex vivo confocal laser scanning microscopy (ex vivo CLSM) is a novel diagnostic method allowing rapid, high-resolution imaging of excised skin samples. Furthermore, fluorescent detection is possible using fluorescent-labelled antibodies. To assess the applicability of ex vivo CLSM in the
Işın Sinem Bağcı et al.
Acta dermato-venereologica, 97(5), 622-626 (2017-01-18)
Linear IgG deposits along the basement membrane of adnexa has been proposed to be useful in the diagnosis of bullous pemphigoid (BP), but no controlled studies have been performed. This study evaluated linear IgG fluorescence of the basement membrane of
Local activation of the complement system in endoneurial microvessels of diabetic neuropathy
Rosoklija G B, et al.
Acta Neuropathologica, 99(1), 55-62 (2000)
Işın Sinem Bağcı et al.
Experimental dermatology, 30(5), 684-690 (2020-12-22)
Ex vivo confocal laser scanning microscopy (CLSM) offers real-time examination of excised tissue in reflectance, fluorescence and digital haematoxylin-eosin (H&E)-like staining modes enabling application of fluorescent-labelled antibodies. We aimed to assess the diagnostic performance of ex vivo CLSM in identifying
IgG
Encyclopedia of Immunology (1998)

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