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C6637

Sigma-Aldrich

Cytochalasin A from Drechslera dematioidea

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1 MG
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1 MG
CHF 147.00

About This Item

Formula empirica (notazione di Hill):
C29H35NO5
Numero CAS:
14110-64-6
Peso molecolare:
477.59
Beilstein:
949521
Numero CE:
237-964-9
Numero MDL:
MFCD00005935
Codice UNSPSC:
12352200
ID PubChem:
24892882
NACRES:
NA.77

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Stato

powder

Livello qualitativo

200

Temperatura di conservazione

−20°C

Stringa SMILE

C[C@@H]1CCCC(=O)\C=C\C(=O)O[C@]23[C@@H](\C=C\C1)[C@H](O)C(=C)[C@@H](C)[C@H]2[C@H](Cc4ccccc4)NC3=O

InChI

1S/C29H35NO5/c1-18-9-7-13-22(31)15-16-25(32)35-29-23(14-8-10-18)27(33)20(3)19(2)26(29)24(30-28(29)34)17-21-11-5-4-6-12-21/h4-6,8,11-12,14-16,18-19,23-24,26-27,33H,3,7,9-10,13,17H2,1-2H3,(H,30,34)/b14-8+,16-15+/t18-,19-,23+,24+,26+,27-,29-/m1/s1
ZMAODHOXRBLOQO-TZVKRXPSSA-N

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Azioni biochim/fisiol

Cytochalasin A reacts with sulfhydryls, and inhibits growth and glucose transport in Saccharomyces.
Cytochalasin A reacts with sulfhydryls, and inhibits growth and glucose transport in Saccharomyces. Cytochalasin A is an oxidizing analog of cytochalsin B.

Altre note

Oxidized analog of cytochalasin B.

Pittogrammi

Skull and crossbonesHealth hazard
GHS06,GHS08

Avvertenze

Danger

Indicazioni di pericolo

H300 + H310 + H330,H361

Classi di pericolo

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Repr. 2

Codice della classe di stoccaggio

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

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Certificati d'analisi (COA)

Lot/Batch Number
0000234989
0000225724
14170301
107M4070V
064M4004V

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Yujiro Higuchi et al.
Biochemical and biophysical research communications, 340(3), 784-791 (2005-12-29)
Endocytosis is an important process for cellular activities. However, in filamentous fungi, the existence of endocytosis has been so far elusive. In this study, we used AoUapC-EGFP, the fusion protein of a putative uric acid-xanthine permease with enhanced green fluorescent
Tehila Hyman et al.
Molecular biology of the cell, 17(1), 427-437 (2005-10-28)
In epithelial cell lines, apical but not basolateral clathrin-mediated endocytosis has been shown to be affected by actin-disrupting drugs. Using electron and fluorescence microscopy, as well as biochemical assays, we show that the amount of actin dedicated to endocytosis is
Kumiko Masai et al.
Bioscience, biotechnology, and biochemistry, 68(7), 1569-1573 (2004-07-28)
The distribution of the secreted protein ribonuclease T1 (RntA) fused with the enhanced green fluorescent protein (EGFP), RntA-EGFP, was visualized in hyphae of Aspergillus oryzae in the presence of a protein transport inhibitor, brefeldin A, cytochalasin A, or nocodazole. During
Naimeh Taheri-Talesh et al.
Molecular biology of the cell, 19(4), 1439-1449 (2008-01-25)
Hyphal tip growth in fungi is important because of the economic and medical importance of fungi, and because it may be a useful model for polarized growth in other organisms. We have investigated the central questions of the roles of
M Riquelme et al.
Protoplasma, 222(3-4), 211-215 (2004-01-10)
It is well established that cytoplasmic microtubules are depolymerized during nuclear division and reassembled as mitotic microtubules. Mounting evidence showing that cytoplasmic microtubules were also involved in apical growth of fungal hyphae posed the question of whether apical growth became
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