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37920

Sigma-Aldrich

6,8-Dihydroxy-1,3-pyrenedisulfonic acid disodium salt

BioReagent, suitable for fluorescence, ≥97.0% (HPCE)

Sinonimo/i:

DHPDS, Disodium 6,8-dihydroxy-1,3-pyrenedisulfonate

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About This Item

Formula empirica (notazione di Hill):
C16H8Na2O8S2
Numero CAS:
61255-63-8
Peso molecolare:
438.34
Beilstein:
8962638
Numero MDL:
MFCD00800283
Codice UNSPSC:
12352106
ID PubChem:
57649723
NACRES:
NA.32

Nome Commerciale

BioReagent

Saggio

≥97.0% (HPCE)

Forma fisica

powder

pKa 

7.33
8.53

Punto di fusione

≥250 °C (lit.)

Solubilità

DMF: soluble
H2O: soluble
methanol: soluble

Fluorescenza

λex 405 nm; λem 456 nm in 0.1 M citrate pH 3.0
λex 458 nm; λem 498 nm in 0.1 M Tris pH 8.0

Compatibilità

suitable for fluorescence

Stringa SMILE

[Na+].[Na+].Oc1cc(O)c2ccc3c(cc(c4ccc1c2c34)S([O-])(=O)=O)S([O-])(=O)=O

InChI

1S/C16H10O8S2.2Na/c17-11-5-12(18)8-2-4-10-14(26(22,23)24)6-13(25(19,20)21)9-3-1-7(11)15(8)16(9)10;;/h1-6,17-18H,(H,19,20,21)(H,22,23,24);;/q;2*+1/p-2
JISMNCQKTAIERN-UHFFFAOYSA-L

Applicazioni

6,8-Dihydroxy-1,3-pyrenedisulfonic acid (DHPDS) is a pH-sensitive dye that may be used to measure pH changes inside cells (pHi). DHPDS is used to create charge transfer complexes for studies on nanostructure assembly.

Confezionamento

Bottomless glass bottle. Contents are inside inserted fused cone.

Altre note

Highly water soluble pH indicator for the physiological range

Pittogrammi

Exclamation mark
GHS07

Avvertenze

Warning

Indicazioni di pericolo

H315,H319,H335

Classi di pericolo

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

dust mask type N95 (US), Eyeshields, Gloves

Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Aron Hakonen et al.
Talanta, 80(5), 1964-1969 (2010-02-16)
This study presents a high-performance ratiometric pH optode based on the fluorophore 6,8-dihydroxypyrene-1,3-disulfonic acid (DHPDS). The two pH-sensitive terminal hydroxy groups of DHPDS facilitated dual excitation/dual emission (F(1): lambda(1,ex)=420 nm, lambda(1,em)=462 nm; F(2): lambda(2,ex)=470 nm, lambda(2,em)=498 nm) properties for ratiometric
Chao Wang et al.
Langmuir : the ACS journal of surfaces and colloids, 26(18), 14509-14511 (2010-08-21)
We have demonstrated a hierarchical self-assembly of the nanoribbons on the basis of the concept of a superamphiphile. A viologen-containing surfactant (RV) and a water-soluble electron donor, 6,8-dihydroxypyrene-1,3-disulfonic acid disodium (DHP), are mixed in water to form a charge transfer
K Hanaoka et al.
Nihon rinsho. Japanese journal of clinical medicine, 50(9), 2048-2053 (1992-09-01)
Since various cellular processes depend on changes in pH, the regulation of intracellular pH (pHi) is important both for the individual cell and for the organism. The mechanisms of the regulation of pHi can be investigated by monitoring pHi. In
F X Felberbauer et al.
Pflugers Archiv : European journal of physiology, 419(2), 215-217 (1991-09-01)
The pH-sensitive fluorescent dye 1,3-dihydroxy-pyrene-6,8-disulfonic acid (DHPDS) was used to measure intracellular pH (pHi) from the surface fluorescence of the isolated perfused rat liver. Monochromatic light from a fluorometer was focused on the liver with a fiber optic, emitted light
O.S. Wolfbeis et al.
Fresenius Journal of Analytical Chemistry, 314, 119-119 (1983)

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