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PHR1028

Supelco

p-Benzochinone

Pharmaceutical Secondary Standard; Certified Reference Material

Sinonimo/i:

Chinone

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About This Item

Formula condensata:
C6H4(=O)2
Numero CAS:
Peso molecolare:
108.09
Beilstein:
773967
Numero CE:
Numero MDL:
Codice UNSPSC:
12352005
ID PubChem:
NACRES:
NA.24

Grado

certified reference material
pharmaceutical secondary standard

Livello qualitativo

agenzia

traceable to USP 1056504

Densità del vapore

3.73 (vs air)

Tensione di vapore

0.1 mmHg ( 25 °C)

CdA

current certificate can be downloaded

Temp. autoaccensione

815 °F

tecniche

HPLC: suitable
gas chromatography (GC): suitable

Punto di fusione

113-115 °C (lit.)

applicazioni

pharmaceutical (small molecule)

Formato

neat

Temperatura di conservazione

2-8°C

Stringa SMILE

O=C1C=CC(=O)C=C1

InChI

1S/C6H4O2/c7-5-1-2-6(8)4-3-5/h1-4H
AZQWKYJCGOJGHM-UHFFFAOYSA-N

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Descrizione generale

1,4-Benzoquinone is a cyclic conjugated diketone. It belongs to the class of quinones, naturally occurring in plants, fungi, and bacteria.
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.

Applicazioni

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Risultati analitici

These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.

Altre note

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Nota a piè di pagina

To see an example of a Certificate of Analysis for this material enter LRAB7811 in the slot below. This is an example certificate only and may not be the lot that you receive.

Prodotti consigliati

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Avvertenze

Danger

Classi di pericolo

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Flam. Sol. 1 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

Organi bersaglio

Respiratory system

Codice della classe di stoccaggio

4.1B - Flammable solid hazardous materials

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

170.6 °F - closed cup

Punto d’infiammabilità (°C)

77 °C - closed cup


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Certificati d'analisi (COA)

Lot/Batch Number

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1623637

Saccarosio

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Sigma-Aldrich

241326

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Saccarosio meets USP testing specifications

Sigma-Aldrich

S3929

Saccarosio

Quinone chemistry and toxicity
Monks JT, et al.
Toxicology and Applied Pharmacology, 112(1), 2-16 (1992)
Rozbeh Baradaran et al.
Nature, 494(7438), 443-448 (2013-02-19)
Complex I is the first and largest enzyme of the respiratory chain and has a central role in cellular energy production through the coupling of NADH:ubiquinone electron transfer to proton translocation. It is also implicated in many common human neurodegenerative
Rifang Luo et al.
ACS applied materials & interfaces, 5(5), 1704-1714 (2013-02-07)
Recent investigations have demonstrated that polydopamine (PDA)-modified surfaces were beneficial to the proliferation of endothelial cells (ECs). In this work, PDA coated 316L stainless steels (316L SS) were thermally treated at 50, 100, and 150 °C respectively (hereafter designated as
Vandana Bhalla et al.
Dalton transactions (Cambridge, England : 2003), 42(4), 975-980 (2012-11-21)
A pentaquinone based compound 3a has been synthesized which undergoes significant fluorescence enhancement in the presence of Zn(2+) ions with a detection limit up to nanomolar range in THF. Further, the zinc ensemble of 3a is evaluated for its anti-oxidizing
H Yamazaki et al.
Drug metabolism and disposition: the biological fate of chemicals, 27(11), 1260-1266 (1999-10-26)
Troglitazone, a new oral antidiabetic drug, is reported to be mostly metabolized to its conjugates and not to be oxidized by cytochrome P-450 (P-450) enzymes. Of fourteen cDNA-expressed human P-450 enzymes examined, CYP1A1, CYP2C8, CYP2C19, and CYP3A4 were active in

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