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Documenti fondamentali

495455

Sigma-Aldrich

Oligomycin

≥90% (mixture of A, B, and C isomers, HPLC), powder, Antibiotic, Calbiochem

Sinonimo/i:

Oligomycin

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10 MG
CHF 201.00

CHF 201.00


Spedizione prevista il29 maggio 2025



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Cambia visualizzazione
10 MG
CHF 201.00

About This Item

Formula empirica (notazione di Hill):
C45H74O11
Numero CAS:
Peso molecolare:
791.06
Numero MDL:
Codice UNSPSC:
12352200
NACRES:
NA.77

CHF 201.00


Spedizione prevista il29 maggio 2025


Nome del prodotto

Oligomycin, A mixture of A, B, and C isomers.

Livello qualitativo

Saggio

≥90% (mixture of A, B, and C isomers, HPLC)

Stato

powder

Produttore/marchio commerciale

Calbiochem®

Condizioni di stoccaggio

OK to freeze

Colore

white

Condizioni di spedizione

ambient

Temperatura di conservazione

−20°C

InChI

1S/C45H74O11/c1-12-34-17-15-13-14-16-27(4)42(51)44(11,53)43(52)32(9)40(50)31(8)39(49)30(7)38(48)26(3)18-21-37(47)54-41-29(6)35(20-19-34)55-45(33(41)10)23-22-25(2)36(56-45)24-28(5)46/h13-15,17-18,21,25-36,38,40-42,46,48,50-51,53H,12,16,19-20,22-24H2,1-11H3/b14-13+,17-15-,21-18+
MNULEGDCPYONBU-ZUSSGZTJSA-N

Descrizione generale

A mixture of A, B, and C isomers. A macrolide antibiotic that inhibits membrane-bound mitochondrial ATP synthase, preventing phosphoryl group transfer. Induces apoptosis in cultured human lymphoblastoid and other mammalian cells.

Azioni biochim/fisiol

Cell permeable: no
Primary Target
Membrane-bound mitochondrial ATPase (F1)
Product does not compete with ATP.
Reversible: no

Attenzione

Toxicity: Irritant (B)

Ricostituzione

Following reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 2 months at -20°C.

Altre note

Wolvetang, E.J., et al. 1994. FEBS Lett.339, 40.
Amoroso, S., et al. 1993. J. Pharmacol. Exp. Ther.264, 515.
Brustovetsky, N.N., et al. 1993. FEBS Lett.315, 233.
Nagamune, H., et al. 1993. Biochim. Biophys. Acta1141, 231.

Note legali

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable


Certificati d'analisi (COA)

Cerca il Certificati d'analisi (COA) digitando il numero di lotto/batch corrispondente. I numeri di lotto o di batch sono stampati sull'etichetta dei prodotti dopo la parola ‘Lotto’ o ‘Batch’.

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Questions

1–2 of 2 Questions  
  1. Could you provide information on the proportions or ratio of Oligomycin A, B, and C in this mixture? Additionally, are the proportions consistent between lots?

    1 answer
    1. The isomer ratio of product 495455 has not been determined. It is known that the total (A+B+C) is greater than or equal to 90 percent.

      Helpful?

  2. As for the oligomycin(495455),what solvent can I use to dissolve it in order to preserve it as long as possible?

    1 answer
    1. Oligomycin is soluble in DMSO at 50 mg/mL, in ethanol at 250 mg/mL, and in acetone at 50 mg/mL. The solution is stable for at least a week at 0-4 °C and for several months when stored frozen in aliquots at -20 °C.

      Helpful?

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