116833

Adenosine 3′,5′-cyclic Monophosphate, 8-(4-Chlorophenylthio)-2′-O-Methyl-, Sodium Salt

A potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC).

• Sinonimo/i: Adenosine 3′,5′-cyclic Monophosphate, 8-(4-Chlorophenylthio)-2′-O-Methyl-, Sodium Salt, 8-CPT-2ʹ-O-Me-cAMP, Na
• Formula empirica (notazione di Hill): C₁₇H₁₆ClN₅O₆PS · Na
• Peso molecolare: 507.82
• Codice UNSPSC: 12352208

Proprietà

• Livello qualitativo: 100
• Saggio: ≥98% (HPLC)
• Forma fisica: lyophilized
• Produttore/marchio commerciale: Calbiochem^®
• Condizioni di stoccaggio: OK to freeze; desiccated (hygroscopic)
• Solubilità: water: 10 mg/mL
• Condizioni di spedizione: ambient
• Temperatura di conservazione: −20°C

Descrizione

Descrizione generale

A potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC) (also called cAMP-guanine nucleotide-exchange factors or cAMP-GEF) in vitro and in vivo. Does not have any effect on protein kinase A (PKA). A useful tool to discriminate between EPAC and PKA. 5 µmol = 2.54 mg. λmax = 282 nm.

A potent, cell-permeable, and specific activator of the exchange protein activated by cyclic AMP (EPAC) [also called cAMP-guanine nucleotide-exchange factors (cAMP-GEF)] in vitro and in vivo. Does not have any effect on protein kinase A (PKA). A useful tool to discriminate between EPAC and PKA.

Note: 5 µmol = 2.54 mg.

Attenzione

Toxicity: Standard Handling (A)

Ricostituzione

Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Altre note

Kang, G., et al. 2003. J. Biol. Chem.278, 8279.
Enserink, J.M., et al. 2002. Nat. Cell Biol., 4, 901.

Note legali

Sold under license of European Patent Application 02/077,219.0.

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informazioni sulla sicurezza

• Codice della classe di stoccaggio: 11 - Combustible Solids
• Classe di pericolosità dell'acqua (WGK): WGK 1
• Punto d’infiammabilità (°F): Not applicable
• Punto d’infiammabilità (°C): Not applicable