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K2755

Sigma-Aldrich

2-Keto-3-deoxyoctonate ammonium salt

≥97%

Sinonimo/i:

3-Deoxyoctulosonic acid, KDO

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1 MG
CHF 86.20
5 MG
CHF 177.00
10 MG
CHF 297.00
50 MG
CHF 1’160.00

CHF 86.20


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Cambia visualizzazione
1 MG
CHF 86.20
5 MG
CHF 177.00
10 MG
CHF 297.00
50 MG
CHF 1’160.00

About This Item

Formula condensata:
C8H14O8 · NH3
Numero CAS:
Peso molecolare:
255.22
Numero MDL:
Codice UNSPSC:
12352100
ID PubChem:
NACRES:
NA.22

CHF 86.20


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Saggio

≥97%

Stato

powder

Temperatura di conservazione

−20°C

Stringa SMILE

N.OCC(O)C1OC(O)(CC(O)C1O)C(O)=O

InChI

1S/C8H14O8.H3N/c9-2-4(11)6-5(12)3(10)1-8(15,16-6)7(13)14;/h3-6,9-12,15H,1-2H2,(H,13,14);1H3
UDJBBKGYARWWNJ-UHFFFAOYSA-N

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Applicazioni

  • Synthesis of KDO Analogues: A significant study focused on the synthesis of analogues of 3-deoxy-D-manno-octulosonic acid (KDO), which includes compounds such as 2-Keto-3-deoxyoctonate ammonium salt. These analogues were evaluated as potential inhibitors of CMP-KDO synthetase, playing a critical role in the development of new therapeutic agents targeting bacterial infections and enhancing understanding of bacterial lipopolysaccharide synthesis (Luthman et al., 1987).

Azioni biochim/fisiol

KDO is a sialic acid that is a component of bacterial lipopolysaccharides and a possible target for antibiotic development.

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

Dispositivi di protezione individuale

Eyeshields, Gloves, type N95 (US)


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