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852228

Sigma-Aldrich

2′-Deoxyguanosine 5′-monophosphate disodium salt hydrate

≥98%

Sinonimo/i:

2′-Deoxy-5′-guanylic acid disodium salt, 5′-dGMP disodium salt

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1 G
CHF 212.00

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1 G
CHF 212.00

About This Item

Formula empirica (notazione di Hill):
C10H12N5Na2O7P · xH2O
Numero CAS:
33430-61-4
Peso molecolare:
391.18 (anhydrous basis)
Numero MDL:
MFCD00150758
Codice UNSPSC:
41106305
ID PubChem:
24888319
NACRES:
NA.22

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Livello qualitativo

100

Saggio

≥98%

Stato

solid

Impurezze

≤4% ethanol

Punto di fusione

>245 °C (dec.) (lit.)

Stringa SMILE

[Na+].[Na+].[H]O[H].NC1=Nc2c(ncn2[C@H]3C[C@H](O)[C@@H](COP([O-])([O-])=O)O3)C(=O)N1

InChI

1S/C10H14N5O7P.2Na.H2O/c11-10-13-8-7(9(17)14-10)12-3-15(8)6-1-4(16)5(22-6)2-21-23(18,19)20;;;/h3-6,16H,1-2H2,(H2,18,19,20)(H3,11,13,14,17);;;1H2/q;2*+1;/p-2/t4-,5+,6+;;;/m0.../s1
HQSJCEYJAGVPJG-BIHLCPNHSA-L

Categorie correlate

Applicazioni

Reactant involved in:
  • Analysis of self-assembling in solution and nucleation / growth of G-qudruplexes
  • Nucleophilic trapping
  • Reductive alkylation

Codice della classe di stoccaggio

11 - Combustible Solids

Classe di pericolosità dell'acqua (WGK)

WGK 3

Punto d’infiammabilità (°F)

Not applicable

Punto d’infiammabilità (°C)

Not applicable

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Certificati d'analisi (COA)

Lot/Batch Number
MKCT8839
MKBD5452
MKBC9168
MKBC3005
05125CJ

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Sigma-Aldrich

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Sigma-Aldrich

854999

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dGTP PCR Grade, sodium salt

Roche

DGTP-RO

dGTP

Adenosine 5′-monophosphate disodium salt ≥99.0% (HPLC)

Sigma-Aldrich

01930

Adenosine 5′-monophosphate disodium salt

Jean L Whittingham et al.
The Biochemical journal, 428(3), 499-509 (2010-04-01)
Plasmodium falciparum is the causative agent of malaria, a disease where new drug targets are required due to increasing resistance to current anti-malarials. TMPK (thymidylate kinase) is a good candidate as it is essential for the synthesis of dTTP, a
Mahmoud Kandeel et al.
Nucleic acids symposium series (2004), (53)(53), 39-40 (2009-09-15)
In Plasmodium falciparum, deoxyguanylate was found to be a substrate for several DNA metabolizing enzymes. Guanylate kinase utilizes dGMP with very low specificity, which is estimated to be the lowest among well-known prokaryotic and eukaryotic enzymes. Furthermore, thymidylate kinase, which
Mariko Higuchi et al.
Journal of structural biology, 173(1), 20-28 (2010-10-05)
MutT distinguishes substrate 8-oxo-dGTP from dGTP and also 8-oxo-dGMP from dGMP despite small differences of chemical structures between them. In this paper we show by the method of molecular dynamics simulation that the transition between conformational substates of MutT is
Mingfeng Li et al.
PloS one, 8(1), e54420-e54420 (2013-02-01)
Free extracellular DNA provides nutrition to bacteria and promotes bacterial evolution by inducing excessive mutagenesis of the genome. To understand the influence of extracellular DNA fragments on D. radiodurans, we investigated cell growth and survival after extracellular DNA or dNMPs
Yancheng Liu et al.
Journal of photochemistry and photobiology. B, Biology, 118, 58-65 (2012-12-12)
Photochemical properties and phototoxicity of Pazufloxacin (PAX) were systematically investigated in aqueous solutions using UV-Vis, fluorescence, laser flash photolysis, pulse radiolysis and SDS-PAGE gel electrophoresis techniques. PAX triplet-state ((3)PAX(*)) absorption spectra (λ(max)=570 nm) was determined. (3)PAX(*) was quenched by PAX
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