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Merck

HTR3A

5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

Sinonimi:
5-HT-3, 5-HT3A, 5-HT3R, 5HT3R, HTR3
Specie:
ID UniProtKB:
ID gene:
  • Human(3359) Summary: The product of this gene belongs to the ligand-gated ion channel receptor superfamily. This gene encodes subunit A of the type 3 receptor for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. This receptor causes fast, depolarizing responses in neurons after activation. It appears that the heteromeric combination of A and B subunits is necessary to provide the full functional features of this receptor, since either subunit alone results in receptors with very low conductance and response amplitude. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(15561) 5-hydroxytryptamine (serotonin) receptor 3A
  • Rat(79246) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • Domestic Rabbit(100009570) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • chicken(428247) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • domestic guinea pig(100135547) 5-hydroxytryptamine (serotonin) receptor 3A
  • Horse(100009690) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • naked mole-rat(101714088) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • sheep(101110536) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • dog(489399) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic
  • cow(617674) 5-hydroxytryptamine (serotonin) receptor 3A
  • domestic cat(101098004) 5-hydroxytryptamine (serotonin) receptor 3A, ionotropic

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Small Molecule - Agonist

N° Catalogo
Descrizione
Specie
Metoclopramide, VETRANAL®, analytical standard,
Specie
human
Metoclopramide, European Pharmacopoeia (EP) Reference Standard,
Specie
human
Metoclopramide hydrochloride, British Pharmacopoeia (BP) Reference Standard,
Specie
human
SR 57227A, solid,
Specie
human
Metoclopramide hydrochloride, solid,
Specie
human

Small Molecule - Allosteric Modulator

N° Catalogo
Descrizione
Specie
DCEBIO, ≥98% (HPLC), solid,
Specie
human

Small Molecule - Antagonist

N° Catalogo
Descrizione
Specie
Serotonina, powder,
Specie
human
Serotonin creatinine sulfate monohydrate, powder,
Specie
human
Ondansetron hydrochloride dihydrate, ≥98% (HPLC), powder,
Specie
human
Ondansetron hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Specie
human
1-Phenylbiguanide, 98%,
Specie
mouse

Antibodies

N° Catalogo
Descrizione
Reattività con
Applicazione
Anti-HTR3A antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reattività con
human
Applicazione
immunohistochemistry
Anti-Serotonin receptor 3A/HTR3A, from rabbit, purified by affinity chromatography,
Reattività con
human
Applicazione
immunohistochemistry
western blot

Small Molecule - Blocker

N° Catalogo
Descrizione
Specie
Trimipramine maleate salt, ≥98% (TLC), powder,
Specie
human
Zimelidine dihydrochloride, solid,
Specie
human

Small Molecule - Inhibitor

N° Catalogo
Descrizione
Specie
S-(+)-Fluoxetine hydrochloride, ≥98% (HPLC), solid,
Specie
human
R-(−)-Fluoxetine hydrochloride, >98% (HPLC), solid,
Specie
human
Fluoxetine hydrochloride, solid,
Specie
human
Reserpine, ,
Specie
human
Sertraline hydrochloride, ≥98% (HPLC),
Specie
human

Small Molecule - Ligand

N° Catalogo
Descrizione
Specie
Nω-Methyl-5-hydroxy­trypt­amine oxalate salt, ≥90% (HPLC),
Specie
human

Small Molecule - Metabolite

N° Catalogo
Descrizione
Specie
5-Hydroxyindole-3-acetic acid, ≥98% (HPLC), crystalline,
Specie
human

Small Molecule - Precursor

N° Catalogo
Descrizione
Specie
5-Hydroxy-L-tryptophan, powder,
Specie
human

esiRNA

N° Catalogo
Descrizione
Specie
MISSION® esiRNA, targeting mouse Htr3a,
Specie
mouse
MISSION® esiRNA, targeting human HTR3A,
Specie
human