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HPLC Analysis of CYP3A Inhibitors on Ascentis® Express RP-Amide

HPLC Analysis of CYP3A Inhibitors on Ascentis® Express RP-Amide application for HPLC

Materialien

Analytische Säule

Produkt-Nr.
Beschreibung
Preisangaben

53913-U

Ascentis® Express RP-Amid, 2,7 μm HPLC-Säule

2.7 μm particle size, L × I.D. 10 cm × 2.1 mm

Komponente der mobilen Phase

Produkt-Nr.
Beschreibung
Preisangaben

70221

Ammoniumformat

eluent additive for LC-MS, LiChropur™, ≥99.0%

Standard

Produkt-Nr.
Beschreibung
Preisangaben

N5536

Nefazodon -hydrochlorid

≥98% (HPLC), solid

S6319

Sertralin -hydrochlorid

≥98% (HPLC)

1279804

Fluoxetin -hydrochlorid

United States Pharmacopeia (USP) Reference Standard

1285909

Fluvoxaminmaleat

United States Pharmacopeia (USP) Reference Standard

PHR1285

Lovastatin

Pharmaceutical Secondary Standard; Certified Reference Material

CONDITIONS

column

Ascentis Express RP-Amide, 10 cm x 2.1 mm I.D., 2.7 μm particles (53913-U)

mobile phase

[A] 20 mM ammonium formate in 50:50 (v/v) water:acetonitrile

flow rate

0.6 mL/min

column temp.

35 °C

detector

ESI(+), m/z 100-600

injection

1 μL

Beschreibung

Hinweis zur Analyse

This application demonstrates the suitability of the Ascentis Express RP Amide for the analysis of CYP3A Inhibitors.

Rechtliche Hinweise

Ascentis is a registered trademark of Merck KGaA, Darmstadt, Germany

Chromatogram Search

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HPLC ColumnsGC Columns & AccessoriesTLC Plates & AdsorbentsSolid Phase Microextraction (SPME)Solid Phase Extraction & QuEChERS

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Small Molecule HPLCLarge Molecule HPLCGas Chromatography (GC)TLCSolid Phase Microextraction (SPME)Solid Phase Extraction (SPE)QuEChERS