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Z2125

Sigma-Aldrich

Zearalenon

fungal mycotoxin

Synonym(e):

F2-Toxin

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About This Item

Empirische Formel (Hill-System):
C18H22O5
CAS-Nummer:
17924-92-4
Molekulargewicht:
318.36
Beilstein:
1350216
MDL-Nummer:
MFCD00133085
UNSPSC-Code:
12191503
PubChem Substanz-ID:
24902175
NACRES:
NA.77

Qualitätsniveau

300

Lagertemp.

−20°C

SMILES String

C[C@H]1CCCC(=O)CCC\C=C\c2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H22O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h3,7,10-12,20-21H,2,4-6,8-9H2,1H3/b7-3+/t12-/m0/s1

InChIKey

MBMQEIFVQACCCH-QBODLPLBSA-N

Angaben zum Gen

mouse ... Esr1(13982)

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Verwandte Kategorien

Biochem./physiol. Wirkung

Zearalenone, a fungal mycotoxin produced by Fusarium, binds the estrogen receptor (ER) and is uterotropic in the newborn rat. It is a common contaminant in cereal grain used for animal and human food, and exerts an estrogenic activity that modulates/disrupts endocrine function in animals and possibly humans.

Piktogramme

Health hazardCorrosion
GHS08,GHS05

Signalwort

Danger

H-Sätze

H314,H361d

Gefahreneinstufungen

Eye Dam. 1 - Repr. 2 - Skin Corr. 1B

Lagerklassenschlüssel

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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α-Zearalanol ~98% (HPLC)

Sigma-Aldrich

Z0292

α-Zearalanol

T-2-Toxin from Fusarium sp., powder, ≥98% (HPLC)

Sigma-Aldrich

T4887

T-2-Toxin

Curvularin from Penicillium citrinum, ≥98% (HPLC)

Sigma-Aldrich

SML0772

Curvularin

Deoxynivalenol -Lösung 100 μg/mL in acetonitrile, analytical standard

Supelco

34124

Deoxynivalenol -Lösung

vibrant-m

ERMAC699

Zearalenon in Acetonitril

D M Sheehan et al.
Teratology, 29(3), 383-392 (1984-06-01)
Fusarium sp. contaminated feedstuffs elicit adverse estrogenic effects in several commercially important animal species via the mycotoxin zearalenone. An estrogenically active synthetic derivative, zearalanol, is used as an anabolic agent in cattle. Since estrogens can irreversibly alter target tissue development
Katarzyna Cieplińska et al.
Toxins, 11(5) (2019-05-30)
Zearalenone is a frequent contaminant of cereals and their by-products in regions with a temperate climate. This toxic molecule is produced naturally by Fusarium fungi in crops. The aim of this study was to determine the influence of low zearalenone
H Leffers et al.
Human reproduction (Oxford, England), 16(5), 1037-1045 (2001-05-02)
We have compared the oestrogenic potency of the synthetic oestrogen Zeranol, used as a growth promoter in meat production, and five related compounds, with the potency of 17beta-oestradiol, diethylstilboestrol (DES), genistein, and Bisphenol-A. The potency was assayed by analysing differences
Kazimierz Obremski et al.
Toxins, 12(6) (2020-05-31)
The aim of the present study was to determine the effect of zearalenone (ZEN), administered per os to gilts at doses equivalent to 50%, 100%, and 150% of no-observed-adverse-effect level (NOAEL) values for 14, 28, and 42 days during weaning
Cristina Juan et al.
Food chemistry, 134(4), 2389-2397 (2013-02-28)
Although analytical methods have been already reported for legislated mycotoxins as trichothecenes and zearalenone (ZON) separately, we describe the optimization of a simple and rapid multimycotoxin method for the determination of a total of 12 mycotoxins simultaneously, nine trichothecenes (NIV
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