V1255

D-Valin

suitable for cell culture, BioReagent

• Synonym(e): (R)-α-Aminoisovaleriansäure, (R)-2-Amino-3-methylbuttersäure
• Lineare Formel: (CH₃)₂CHCH(NH₂)CO₂H
• CAS-Nummer: 640-68-6
• Molekulargewicht: 117.15
• Beilstein: 1721135
• EG-Nummer: 211-368-9
• MDL-Nummer: MFCD00064219
• UNSPSC-Code: 12352209
• PubChem Substanz-ID: 24900713
• NACRES: NA.75

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Produktlinie: BioReagent
• Form: powder
• Methode(n): cell culture | mammalian: suitable
• mp (Schmelzpunkt): >295 °C (subl.) (lit.)
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: CC(C)[C@@H](N)C(O)=O
• InChI: 1S/C5H11NO2/c1-3(2)4(6)5(7)8/h3-4H,6H2,1-2H3,(H,7,8)/t4-/m1/s1
• InChIKey: KZSNJWFQEVHDMF-SCSAIBSYSA-N

Beschreibung

Allgemeine Beschreibung

L-Valine is an essential non-polar amino acid. D-Valine is the non-proteinogenic isomer of valine.

Anwendung

D-Valine has been used as a supplement in:

• Dulbecco′s modified Eagle′s medium (DMEM)/Nutrient Mixture F-12 Ham (F-12) for mice renal proximal tubule cell (RPTC) culture
• endothelial cell growth medium MV2 for rat lung microvascular endothelial cell (RLMEC) culture
• DMEM/F-12 for mouse tracheal epithelial cell (MTEC) culture

Biochem./physiol. Wirkung

D-Valine has a broad range of industrial applications such as semi-synthetic veterinary antibiotics, pharmaceutical drugs, and agricultural pesticides.

D-valine is used in cell culture as a selective inhibitor of cell proliferation, wherein it inhibits cells that lack the enzyme D-amino acid oxidase. Historically D-valine has been used to inhibit fibroblast growth while allowing selective growth of epithelial cells.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)