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V0131

Sigma-Aldrich

Vasoactive Intestinal Peptide Fragment 1-12 human, porcine, rat

≥97% (HPLC)

Synonym(e):

VIP 1-12

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About This Item

Empirische Formel (Hill-System):
C61H88N18O22
CAS-Nummer:
120928-03-2
Molekulargewicht:
1425.46
MDL-Nummer:
MFCD00133921
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24900690
NACRES:
NA.26

Produktbezeichnung

Vasoactive Intestinal Peptide Fragment 1-12 human, porcine, rat, ≥97% (HPLC)

Qualitätsniveau

200

Assay

≥97% (HPLC)

Form

solid

UniProt-Hinterlegungsnummer

P01282

Anwendung(en)

cell analysis

Lagertemp.

−20°C

SMILES String

CC(C)C(NC(=O)C(C)NC(=O)C(CC(O)=O)NC(=O)C(CO)NC(=O)C(N)Cc1cnc[nH]1)C(=O)NC(Cc2ccccc2)C(=O)NC(C(C)O)C(=O)NC(CC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(Cc3ccc(O)cc3)C(=O)NC(C(C)O)C(=O)NC(CCCNC(N)=N)C(O)=O

InChI

1S/C61H88N18O22/c1-27(2)46(77-49(89)28(3)69-51(91)40(22-44(85)86)73-56(96)42(25-80)76-50(90)35(62)20-33-24-66-26-68-33)57(97)74-38(18-31-10-7-6-8-11-31)55(95)79-48(30(5)82)59(99)75-41(23-45(87)88)53(93)72-39(21-43(63)84)52(92)71-37(19-32-13-15-34(83)16-14-32)54(94)78-47(29(4)81)58(98)70-36(60(100)101)12-9-17-67-61(64)65/h6-8,10-11,13-16,24,26-30,35-42,46-48,80-83H,9,12,17-23,25,62H2,1-5H3,(H2,63,84)(H,66,68)(H,69,91)(H,70,98)(H,71,92)(H,72,93)(H,73,96)(H,74,97)(H,75,99)(H,76,90)(H,77,89)(H,78,94)(H,79,95)(H,85,86)(H,87,88)(H,100,101)(H4,64,65,67)

InChIKey

OZQVVUDUPMJWPH-UHFFFAOYSA-N

Angaben zum Gen

human ... VIP(7432)

Amino Acid Sequence

His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-Thr-Arg

Biochem./physiol. Wirkung

Ligand for CD4 receptor.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
118K8724
048K1292
067K1846
076K13691
095K11621

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Die Dokumentenbibliothek aufrufen

K J Sung et al.
Neuropeptides, 33(6), 435-446 (2000-02-05)
It is well known that psoriasis, an immunogenetic cutaneous disorder whose major pathogenic findings are epidermal hyperplasia and T-cell infiltration, is aggravated by psychological stresses. Although the exact mechanism is not yet clarified, antidromic secretion of neuropeptides by cutaneous nerve
F Séjourné et al.
The American journal of physiology, 273(1 Pt 2), R287-R292 (1997-07-01)
The purpose of this study was to begin to determine the mechanisms underlying vasodilation elicited by vasoactive intestinal peptide (VIP) in sterically stabilized liposomes (SSL) in the in situ peripheral microcirculation. Using intravital microscopy, we found that suffusion of VIP
S Chakder et al.
The Journal of pharmacology and experimental therapeutics, 266(1), 392-399 (1993-07-01)
Because no significant information exists regarding the structure-activity of vasoactive intestinal polypeptide (VIP) to gut smooth muscle, we performed functional studies in vitro on opossum internal anal sphincter (IAS) smooth muscle strips and supplemented them with binding studies to assess
M Ichinose et al.
Regulatory peptides, 54(2-3), 457-466 (1994-12-15)
The effect of VIP on phagocytosis in peritoneal macrophages was examined by means of flow cytometry (FCM). This assay revealed that VIP suppressed phagocytosis in a dose-dependent manner. VIP(1-12) did not suppress phagocytosis. VIP(10-28) was more suppressive than VIP(1-28). A
P Sacerdote et al.
Journal of neuroscience research, 18(1), 102-107 (1987-01-01)
A five-amino-acid (TDNYT) sequence of vasoactive intestinal polypeptide (VIP) shares homology with the proposed attachment sequences of the human immunodeficiency virus (HIV). Synthetic peptides with these sequences have previously been shown to block viral envelope (gp120) binding and HIV infectivity

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