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SRP6309

Sigma-Aldrich

Proteinase 3 from human neutrophils

≥95% (SDS-PAGE)

Synonym(e):

AGP7, C-ANCA antigen, Leukocyte proteinase 3, Neutrophil proteinase 4, P29, Wegener autoantigen

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About This Item

UNSPSC-Code:
12352200

Biologische Quelle

human

Assay

≥95% (SDS-PAGE)

Form

frozen liquid

Mol-Gew.

29 kDa

Verpackung

pkg of 25 μg

UniProt-Hinterlegungsnummer

P24158

Versandbedingung

dry ice

Lagertemp.

−70°C

Angaben zum Gen

human ... AGP7(5657)

Allgemeine Beschreibung

Proteinase 3 is one of the serine proteinases localized in azurophil granules of polymorphonuclear leukocytes. It has been identified as the autoantigen of Wegener granulomatosis, a systemic vasculitis complicated by melomonocyte proliferation. It exhibits proteolytic activity towards a range of substrates. It is physiologically inhibited by α1-antitrypsin. The protein has been described as having antibiotic and growth-promoting properties and causing emphysema when administered by tracheal insufflation. Proteinase 3 (PR-3) is also known as myeloblastin and p29b.

Physikalische Form

Frozen in 50 mM MES, pH 4.5 with 700 mM NaCl.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number
5M18L72900
6J30L72900
6C13L72900
5K30L72900

Die passende Version wird nicht angezeigt?

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Sigma-Aldrich

T9326

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Questions

  1. Could you please provide the volume and concentration of the product with the code SRP6309-25ug?

    1 answer

    1. The volume and concentration are lot specific.

      Examples below:
      Lot: 6J30L72900
      Volume: 23.6 µL
      Concentration: 1.06 mg/mL

      Lot: 8A10L72900
      Volume: 22.9 µL
      Concentration: 1.0917 mg/mL

      The concentration of the newer lots should be on the vial label. The volume can then be calculated using the lot specific concentration and the pack size, which is 25 µg.

      Helpful?

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