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SML0463

Sigma-Aldrich

BPD

≥98% (HPLC)

Synonym(e):

3-(1,3-benzodioxol-5-yl)-4-phenyl-2,5-Furandione

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About This Item

Empirische Formel (Hill-System):
C17H10O5
CAS-Nummer:
213481-12-0
Molekulargewicht:
294.26
MDL-Nummer:
MFCD22666591
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329824741

Assay

≥98% (HPLC)

Form

powder

Lagerbedingungen

desiccated

Farbe

white to beige

Löslichkeit

DMSO: 15 mg/mL (clear solution)

Lagertemp.

−20°C

SMILES String

O=C1OC(=O)C(c2ccc3OCOc3c2)=C1c4ccccc4

InChI

1S/C17H10O5/c18-16-14(10-4-2-1-3-5-10)15(17(19)22-16)11-6-7-12-13(8-11)21-9-20-12/h1-8H,9H2

InChIKey

IMHGOAWBSJVILI-UHFFFAOYSA-N

Biochem./physiol. Wirkung

BPD inhibits LPS-induced NF-kB signaling by inactivation of TAK-1. BPD is also known to inhibit the expression and activity of COX-2.

Leistungsmerkmale und Vorteile

This compound is featured on the Cytokine Receptors (Interleukin-1 Receptor/TIR Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Piktogramme

Exclamation markEnvironment
GHS07,GHS09

Signalwort

Warning

H-Sätze

H302,H400

P-Sätze

P273

Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Acute 1

Lagerklassenschlüssel

13 - Non Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

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Graciela Sotelo et al.
BMC evolutionary biology, 20(1), 23-23 (2020-02-11)
The flat periwinkles, Littorina fabalis and L. obtusata, are two sister species widely distributed throughout the Northern Atlantic shores with high potential to inform us about the process of ecological speciation in the intertidal. However, whether gene flow has occurred
Carla Sharp et al.
Assessment, 26(6), 1014-1029 (2018-07-14)
DSM-5 (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition) Section II criteria for borderline personality disorder (BPD) lack developmental operationalization. The aim of the current study was to evaluate whether DSM criteria operate similarly across adolescents and adults to
Ilaria Cataldo et al.
Research in developmental disabilities, 82, 27-38 (2017-10-17)
Oxytocin plays an important role in the modulation of social behavior in both typical and atypical contexts. Also, the quality of early parental care sets the foundation for long-term psychosocial development. Here, we review studies that investigated how oxytocin receptor
Johanna Köhling et al.
Journal of personality disorders, 30(6), 776-795 (2015-12-02)
The quality of depression in borderline personality disorder (BPD) was reported to differ from that in patients with major depressive disorder (MDD) only. However, little is known about affect dynamics in "borderline-depression." The authors assessed affective instability and reactivity in
Niall M McGowan et al.
Translational psychiatry, 9(1), 195-195 (2019-08-23)
Bipolar disorder (BD) and borderline personality disorder (BPD) are two psychiatric disorders with overlapping features that can be challenging to separate diagnostically. Growing evidence suggests that circadian rhythm disturbances are associated with psychiatric illness, however circadian patterns of behaviour have
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