SAB5700627

Anti-TNF-α antibody produced in rabbit

• Synonym(e): DIF, TNF, TNF alpha, TNF-alpha, TNFA, TNFSF2, TNLG1F
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Form: buffered aqueous solution
• Mol-Gew.: 25
• Speziesreaktivität: human, rat, mouse
• Konzentration: 0.46 mg/ml
• Methode(n): immunofluorescence: 1:50-1:200; immunohistochemistry: 1:50-1:200; western blot: 1:1000-1:2000
• UniProt-Hinterlegungsnummer: P01375
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... TNF(7124)

Beschreibung

Allgemeine Beschreibung

This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell proliferation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1-233 of human TNF (NP_000585.2).

Physikalische Form

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

Lagerung und Haltbarkeit

Store at -20℃. Avoid freeze / thaw cycles.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable