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Merck

SAB4502954

Sigma-Aldrich

Anti-TGF β1 antibody produced in rabbit

affinity isolated antibody

Synonym(e):

CED, DPD1, TGF-β 1, diaphyseal dysplasia 1, progressive

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Konjugat

unconjugated

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Mol-Gew.

antigen 44 kDa

Speziesreaktivität

mouse, rat, human

Konzentration

~1 mg/mL

Methode(n)

ELISA: 1:5000
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Anwendung(en)

research pathology

Versandbedingung

wet ice

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... TGFB1(7040)

Allgemeine Beschreibung

Anti-TGF β1 Antibody detects endogenous levels of total TGF β1 protein.
The TGF β1 (transforming growth factor β1) gene is mapped to human chromosome 19q13.2.

Immunogen

The antiserum was produced against synthesized peptide derived from human TGF beta1.

Immunogen Range: 336-385

Anwendung

Anti-TGF β1, C-Terminal antibody produced in rabbit has been used in immunohistochemistry and Western blot analysis.

Biochem./physiol. Wirkung

TGF β1 (transforming growth factor β1) mediates cell vitality, proliferation, epithelial–mesenchymal transition and promotes angiogenesis. TGF β1 controls the process of apoptosis, organ development and bone formation.

Leistungsmerkmale und Vorteile

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physikalische Form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

nwg

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Fucoidan exerts protective effects against diabetic nephropathy related to spontaneous diabetes through the NF-?B signaling pathway in vivo and in vitro.
Wang Y
International Journal of Molecular Medicine, 35(4), 1067-1073 (2015)
Analysis of polymorphic TGFB1 codons 10, 25, and 263 in a German patient group with non-syndromic cleft lip, alveolus, and palate compared with healthy adults.
Stoll C
BMC Medical Genetics, 5:15, 1-9 (2004)
CD44v6 promotes ?-catenin and TGF-? expression, inducing aggression in ovarian cancer cells.
Wang J
Molecular Medicine Reports, 11(5), 3505-3510 (2015)
Ken Yoshida et al.
Stem cells translational medicine, 7(12), 893-905 (2018-10-01)
Serum used in culture medium brings risks of immune reactions or infections and thus may hinder using ex vivo expanded mesenchymal stem cells (MSCs) for medical treatment. Here, we cultured MSCs in a serum-free medium (SF-MSCs) and in a medium
Loss-of-function of miR-142 by hypermethylation promotes TGF-?-mediated tumour growth and metastasis in hepatocellular carcinoma.
Yu Q
Cell Proliferation, 50(6) (2017)

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