S1250

(−)-α-Santonin

≥99%

• Synonym(e): (3S,5aS,9bS)-3a,5,5a,9b-Tetrahydro-3,5a,9-trimethyl-naphtho[1,2-b]furan-2,8(3H)-dion, Semenen
• Empirische Formel (Hill-System): C₁₅H₁₈O₃
• CAS-Nummer: 481-06-1
• Molekulargewicht: 246.30
• Beilstein: 89489
• EG-Nummer: 207-560-7
• MDL-Nummer: MFCD00135865
• UNSPSC-Code: 12352204
• PubChem Substanz-ID: 24899466
• NACRES: NA.83

Eigenschaften

• Assay: ≥99%
• mp (Schmelzpunkt): 172-173 °C (lit.)
• Lagertemp.: 2-8°C
• SMILES String: C[C@H]1[C@@H]2CC[C@@]3(C)C=CC(=O)C(C)=C3[C@H]2OC1=O
• InChI: 1S/C15H18O3/c1-8-10-4-6-15(3)7-5-11(16)9(2)12(15)13(10)18-14(8)17/h5,7-8,10,13H,4,6H2,1-3H3/t8-,10-,13-,15-/m0/s1
• InChIKey: XJHDMGJURBVLLE-BOCCBSBMSA-N

Beschreibung

Allgemeine Beschreibung

(−)-α-Santonin is a sesquiterpene lactone. It is found in the genus Artemisia.[1]

Anwendung

(−)-α-Santonin has been used as a eudesmane-type sesquiterpene to study its effects on impairment of 231MFP breast cancer cell survival.[2]

Biochem./physiol. Wirkung

(−)-α-Santonin exhibits anti-helminthic properteis.[1] It exhibits therapeutic effects against intestinal round worms.[3]

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H301 + H311 + H331
• P-Sätze: P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges