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Sigma-Aldrich

Selenocystamine dihydrochloride

>98% (TLC), suitable for ligand binding assays

Synonym(e):

2,2′-diselenobis-Ethanamine hydrochloride (1:2)

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About This Item

Empirische Formel (Hill-System):
C4H12N2Se2 · 2HCl
CAS-Nummer:
3542-13-0
Molekulargewicht:
318.99
MDL-Nummer:
MFCD00035445
UNSPSC-Code:
12352116
PubChem Substanz-ID:
24899440
NACRES:
NA.26

product name

Selenocystamine dihydrochloride, powder

Assay

>98% (TLC)

Form

powder

Methode(n)

ligand binding assay: suitable

Farbe

yellow to orange

Löslichkeit

H2O: soluble, clear to slightly hazy

SMILES String

NCC[Se][Se]CCN.[H]Cl.[H]Cl

InChI

1S/C4H12N2Se2.ClH/c5-1-3-7-8-4-2-6;/h1-6H2;1H

InChIKey

PKRYDZYGNSZBHO-UHFFFAOYSA-N

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Allgemeine Beschreibung

Selenocystamine dihydrochloride has a potential to block the activity of influenza A and B virus associated RNA-dependent RNA polymerase enzyme.

Anwendung

Selenocystamine dihydrochloride has been used to determine its effect on PP2A phosphatase activity in vitro. It has also been used as a catalyst for a disulfide-cleaving reagent, dithiothreitol (DTT).

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - STOT RE 2

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges

Analysenzertifikate (COA)

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M S Stewart et al.
Free radical biology & medicine, 26(1-2), 42-48 (1999-01-16)
The cancer chemopreventive effect of selenium cannot be fully accounted for by the role of selenium as a component of the antioxidant enzyme glutathione peroxidase, which suggests that chemoprevention occurs by another mechanism. Several studies have shown that thiol oxidation
T Tabatabaie et al.
Toxicology and applied pharmacology, 141(2), 389-393 (1996-12-01)
Chronic benzaldehyde exposure is known to cause central nervous system (CNS) disturbances. Previous studies have shown that benzaldehyde causes the formation of reactive oxygen species (ROS) in rat synaptosomal fractions. Benzaldehyde has also been implicated in ROS formation in the
Megan C Frost et al.
Biomaterials, 26(14), 1685-1693 (2004-12-04)
The current state-of-the-art with respect to the preparation, characterization and biomedical applications of novel nitric oxide (NO) releasing or generating polymeric materials is reviewed. Such materials show exceptional promise as coatings to prepare a new generation of medical devices with
L Chen et al.
Free radical biology & medicine, 19(6), 713-724 (1995-12-01)
A selenium (Se)-containing immunoconjugate of a human anti-erythrocyte membrane antibody (Ab-Se) has been synthesized via oxidation of the carbohydrate moieties of the antibody and covalent coupling with selenocystamine. The isolated Ab-Se immunoconjugate is shown to be more hemolytic than is
Glutathione peroxidase activity of D,L-seleno-cystine and selenocystamine.
K Yasuda et al.
Biochemical and biophysical research communications, 96(1), 243-249 (1980-09-16)
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